225385-05-7

Basic information

• Product Name: 2-Bromo-7-chloro-thieno[3...
• Synonyms: 2-Bromo-7-chloro-thieno[3...;2-Bromo-7-chlorothieno[3,2-b]pyridine;Thieno[3,2-b]pyridine, 2-broMo-7-chloro-
• CAS NO: 225385-05-7
• Molecular Formula: C₇H₃BrClNS
• Molecular Weight: 248.52742
• EINECS: 1312995-182-4
• Mol File: 225385-05-7.mol

Chemical Properties

• Boiling Point: 312.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.849±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 2.07±0.40(Predicted)
• CAS DataBase Reference: 2-Bromo-7-chloro-thieno[3...(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-7-chloro-thieno[3...(225385-05-7)
• EPA Substance Registry System: 2-Bromo-7-chloro-thieno[3...(225385-05-7)

Safety Data

• Hazardous Substances Data: 225385-05-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-7-chloro-thieno[3,2-b]pyridine is used as a key intermediate in the synthesis of new drugs. Its unique structure and halogen substituents contribute to the development of molecules with specific biological activities, potentially leading to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-7-chloro-thieno[3,2-b]pyridine serves as a precursor for the production of pesticides. Its chemical properties, including the presence of halogens, may enhance the effectiveness of these compounds in controlling pests and diseases in agriculture.
Both applications capitalize on the compound's distinctive structural features and chemical versatility, making it a valuable asset for research and development in creating innovative products with improved efficacy and selectivity.

Upstream product

• 69627-03-8 7-chlorothieno[3,2-b]pyridine 
• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 

Downstream Products

• 225381-84-0 N-(6-bromo-thieno[3,2-d]pyrimidin-4-yl)-N'-(4-methoxy-phenyl)-benzene-1,4-diamine 
• 875339-25-6 2-Bromo-7-(2-fluoro-4-nitro-phenoxy)-thieno[3,2-b]pyridine 
• 1228102-90-6 4-(7-(3-(4-methoxybenzyloxy)phenylamino)thieno[3,2-b]pyridin-2-yl)benzaldehyde 
• 1228102-91-7 3-(7-(3-(4-methoxybenzyloxy)phenylamino)thieno[3,2-b]pyridin-2-yl)benzaldehyde 
• 1228103-34-1 N-(3-(4-methoxybenzyloxy)phenyl)-2-(4-(piperidin-1-ylmethyl)phenyl)thieno[3,2-b]pyridin-7-amine 
• 1228102-50-8 3-(2-(4-(piperidin-1-ylmethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol trifluoroacetic acid 
• 1228103-41-0 N-(3-(4-methoxybenzyloxy)phenyl)-2-(3-(piperidin-1-ylmethyl)phenyl)thieno[3,2-b]pyridin-7-amine 
• 1228102-89-3 2-bromo-N-(3-(4-methoxybenzyloxy)phenyl)thieno[3,2-b]pyridin-7-amine 

Relevant articles and documents

Heterocyclic compound and preparation method thereof

The invention discloses a compound shown in the formula (A), or a stereisomer thereof, or medically acceptable salt thereof, or a solvate thereof. The new compound shown in the formula (A) is good inURAT1 inhibitory activity and provides new medical possibilities for clinical treatment of diseases related to abnormal URAT1 activity.

ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

The present invention is for the anti-inflammatory compounds that have an inhibitory activity against protein tyrosine kinases and their pharmaceutical composition(s) containing the compound as the active ingredient. Since the compounds of the present invention can inhibit multiple protein kinases associated with inflammatory diseases and immune disorders, they are useful for their prevention or treatment.

Inhibitors of VEGF receptor and HGF receptor signaling

The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions

INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING

The invention relates to the inhibition of vascular endothelial growth factor (VEGF) receptor signaling and hepatocyte growth factor (HGF) receptor signaling. The invention provides compounds and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions

Thienopyrimidine and thienopyridine derivatives useful as anticancer agents

The invention relates to compounds of the formulas 1 and 2 and to pharmaceutically acceptable salts and hydrates thereof, wherein X1, R1, R2and R11are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formulas 1 and 2 and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formulas 1 and 2.