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CAS

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22567-36-8

(-)-ALPHA-BISABOLOL, also known as levomenol, is a naturally occurring chemical compound predominantly found in the essential oil of German Chamomile (Matricaria recutita) and the bark of the Candeia tree (Eremanthus erythropappus) in South America. It is widely recognized for its significant anti-inflammatory and antimicrobial properties, which contribute to its use in various cosmetic and medicinal products. These properties make it a valuable ingredient for soothing, healing, and protecting the skin. Additionally, (-)-alpha-bisabolol is being evaluated for potential applications in cancer therapies due to its cytotoxic effect on certain types of human cancer cells. It is considered non-toxic and non-irritating, making it safe for topical use.

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  • (3S,6S)-2,2,6-trimethyl-6-[(1S)-4-methylcyclohex-3-en-1-yl]oxan-3-ol

    Cas No: 22567-36-8

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  • 22567-36-8 Structure

  • Basic information

    1. Product Name: (-)-ALPHA-BISABOLOL
    2. Synonyms: BISABOLOL, A-(-)-;BISABOLOL OXIDE A;CAMILLOL;HYDAGEN B;LEVOMENOL;DRAGOSANTOL;A-(-)-BISABOLOL;2,2,6-Trimethyl-6-(4-methyl-3-cyclohexen-1-yl)tetrahydro-2H-pyran-3-ol
    3. CAS NO:22567-36-8
    4. Molecular Formula: C15H26O2
    5. Molecular Weight: 238.37
    6. EINECS: 245-086-2
    7. Product Categories: N/A
    8. Mol File: 22567-36-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 327.7±42.0℃ (760 Torr)
    3. Flash Point: 125.9±22.1℃
    4. Appearance: /
    5. Density: 0.982±0.06 g/cm3 (20 ºC 760 Torr)
    6. Refractive Index: N/A
    7. Storage Temp.: ?20°C
    8. Solubility: N/A
    9. PKA: 14.51±0.60(Predicted)
    10. CAS DataBase Reference: (-)-ALPHA-BISABOLOL(CAS DataBase Reference)
    11. NIST Chemistry Reference: (-)-ALPHA-BISABOLOL(22567-36-8)
    12. EPA Substance Registry System: (-)-ALPHA-BISABOLOL(22567-36-8)

  • Safety Data

    1. Hazard Codes: N
    2. Statements: 51/53
    3. Safety Statements: 61
    4. RIDADR: UN3077 9/PG 3
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 22567-36-8(Hazardous Substances Data)

22567-36-8 Usage

Uses

Used in Cosmetic Industry:
(-)-ALPHA-BISABOLOL is used as an active ingredient in skincare products for its soothing and healing properties. It helps to calm irritated skin, reduce inflammation, and promote skin regeneration.
Used in Pharmaceutical Industry:
(-)-ALPHA-BISABOLOL is used as a medicinal component in various topical formulations, such as creams, ointments, and balms, to alleviate skin inflammation and promote wound healing.
Used in Cancer Therapy Research:
(-)-ALPHA-BISABOLOL is being investigated as a potential cytotoxic agent against certain types of human cancer cells, with the aim of developing new cancer treatment options.
Used in Safety Assessments:
(-)-ALPHA-BISABOLOL is used in safety assessments to determine its non-toxic and non-irritating properties, ensuring its suitability for topical applications in skincare and pharmaceutical products.

Check Digit Verification of cas no

The CAS Registry Mumber 22567-36-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,5,6 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 22567-36:
(7*2)+(6*2)+(5*5)+(4*6)+(3*7)+(2*3)+(1*6)=108
108 % 10 = 8
So 22567-36-8 is a valid CAS Registry Number.

22567-36-8 Well-known Company Product Price

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  • Sigma-Aldrich

  • (00630590)  BisabololoxideA  primary pharmaceutical reference standard

  • 22567-36-8

  • 00630590-25MG

  • 6,224.40CNY

  • Detail

22567-36-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (3S,6S)-2,2,6-trimethyl-6-[(1S)-4-methylcyclohex-3-en-1-yl]oxan-3-ol

1.2 Other means of identification

Product number -
Other names bisabololoxide A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22567-36-8 SDS

22567-36-8Upstream product

22567-36-8Relevant articles and documents

On the Stereochemistry of the Bisaboloids from Matricaria chamomilla L.

Flaskamp, Elmar,Nonnenmacher, Gerhard,Zimmermann, Gottfried,Isaac, Otto

, p. 1023 - 1030 (2007/10/02)

The stereochemistry of the bisaboloids in chamomile - with the exception of bisabololoxide C - has been elucidated.The in-vitro-examination of the mutual convertibilities of some bisaboloids gave evidence for the stereochemical accordance of the common chiral centres of all the bisaboloids.The absolute configurations of the remaining third asymmetric carbon atoms in bisabololoxide A and B have been determined by NMR spectrometric studies in comparison with their unnatural semisynthetic epimers.All the stereogenic centres of the bisabololoxides A and B, of (-)-α-bisabolol and of bisabolonoxide A turn out to be S-configurated. - Key words: Matricaria chamomilla L., Bisaboloids, 13C NMR Spectra, Shift-Reagents

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