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22583-90-0

1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride is a chemical compound with the chemical formula C12H17N · HCl. It is a hydrochloride salt form of a naphthalenamine derivative, known for its role as an intermediate in the synthesis of pharmaceutical and organic compounds. 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride is characterized by its potential applications in the production of medications and drugs, as well as its utility in chemical research and development.

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  • 22583-90-0 Structure

  • Basic information

    1. Product Name: 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride
    2. Synonyms: 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride;1,2,3,4-Tetrahydro-N-methyl-2-phthalemine hydrochloride;N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-2-AMINE HYDROCHLORIDE
    3. CAS NO:22583-90-0
    4. Molecular Formula: C11H15N*ClH
    5. Molecular Weight: 197.7
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 22583-90-0.mol

  • Chemical Properties

    1. Melting Point: 212 °C
    2. Boiling Point: 296.7oC at 760 mmHg
    3. Flash Point: 133.3oC
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 0.00106mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride(22583-90-0)
    12. EPA Substance Registry System: 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride(22583-90-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 22583-90-0(Hazardous Substances Data)

22583-90-0 Usage

Uses

Used in Pharmaceutical Industry:
1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride is used as a chemical intermediate for the synthesis of various medications and drugs. Its unique structure allows it to be a key component in the development of new pharmaceutical compounds, contributing to the advancement of medical treatments.
Used in Chemical Research and Development:
In the field of chemical research and development, 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride serves as a valuable compound for exploring new chemical reactions and syntheses. Its properties and reactivity make it a useful tool for scientists and researchers in discovering novel applications and expanding the frontiers of chemical knowledge.
It is crucial to handle and store 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine hydrochloride with care due to its potential health and safety risks if not used properly. Proper handling protocols and safety measures should be strictly followed to ensure the well-being of individuals involved in its production, use, and storage.

Check Digit Verification of cas no

The CAS Registry Mumber 22583-90-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,5,8 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22583-90:
(7*2)+(6*2)+(5*5)+(4*8)+(3*3)+(2*9)+(1*0)=110
110 % 10 = 0
So 22583-90-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H15N.ClH/c1-12-11-7-6-9-4-2-3-5-10(9)8-11;/h2-5,11-12H,6-8H2,1H3;1H

22583-90-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine,hydrochloride

1.2 Other means of identification

Product number -
Other names N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22583-90-0 SDS

22583-90-0Downstream Products

22583-90-0Relevant articles and documents

Discovery and structural analyses of S-adenosyl-l-homocysteine hydrolase inhibitors based on non-adenosine analogs

Nakao, Akira,Suzuki, Hiroko,Ueno, Hiroaki,Iwasaki, Hiroshi,Setsuta, Tomofumi,Kashima, Akiko,Sunada, Shinji

, p. 4952 - 4969 (2015/08/03)

Optimization of a new series of S-adenosyl-l-homocysteine hydrolase (AdoHcyase) inhibitors based on non-adenosine analogs led to very potent compounds 14n, 18a, and 18b with IC50 values of 13 ± 3, 5.0 ± 2.0, and 8.5 ± 3.1 nM, respectively. An X-ray crystal structure of AdoHcyase with NAD+ and 18a showed a novel open form co-crystal structure. 18a in the co-crystals formed intramolecular eight membered ring hydrogen bond formations. A single crystal X-ray structure of 14n also showed an intramolecular eight-membered ring hydrogen bond interaction.

THERAPEUTIC AGENT FOR CEREBRAL INFARCTION

-

, (2012/08/08)

The invention provides a therapeutic drug for ischemic stroke. The therapeutic drug has the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof, as an active ingredient.

Probing the proposed phenyl-A region of the sigma-1 receptor.

Ablordeppey, Seth Y,Fischer, James B,Law,Glennon, Richard A

, p. 2759 - 2765 (2007/10/03)

The proposed phenyl-A region of sigma (sigma) receptors accommodates several structural features. In this study we explored the possibility that appropriate structural features located at the phenyl-A region of sigma receptor sites could lead to more potent and selective agents for the sigma receptor subtypes. By keeping the phenyl-B substituent as the optimum omega-phenylpentyl moiety, and varying substituents in the phenyl-A region, we have observed changes in binding potency and selectivity at the sigma receptor subtypes. SAR for the binding of these compounds at sigma-2 sites was also examined.

Bicyclo-substituted phenylacetonitrile derivatives

-

, (2008/06/13)

The invention relates to compounds of the formula: STR1 which are useful cardiovascular agents.

Bicyclo-substituted phenylacetonitrile derivatives

-

, (2008/06/13)

The invention relates to compounds of the formula: STR1 which are useful cardiovascular agents.

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