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3-(morpholin-4-yl)-1,2-benzoisothiazole is a chemical compound with the molecular formula C10H10N2OS. It is a derivative of benzoisothiazole, featuring a morpholine group attached to the 3-position of the benzene ring. 3-(morpholin-4-yl)-1,2-benzoisothiazole is known for its potential applications in the pharmaceutical and chemical industries, particularly as a building block for the synthesis of various drugs and agrochemicals. Its structure combines the properties of both benzoisothiazole, which is recognized for its diverse biological activities, and morpholine, a cyclic amine that can enhance solubility and stability in pharmaceutical compounds. The compound's specific role in these applications is due to its ability to form stable intermediates and its potential to modulate biological targets, although further research is needed to fully understand its therapeutic potential and safety profile.

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  • 22801-59-8 Structure
  • Basic information

    1. Product Name: 3-(morpholin-4-yl)-1,2-benzoisothiazole
    2. Synonyms: 3-(morpholin-4-yl)-1,2-benzoisothiazole
    3. CAS NO:22801-59-8
    4. Molecular Formula:
    5. Molecular Weight: 220.295
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 22801-59-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(morpholin-4-yl)-1,2-benzoisothiazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(morpholin-4-yl)-1,2-benzoisothiazole(22801-59-8)
    11. EPA Substance Registry System: 3-(morpholin-4-yl)-1,2-benzoisothiazole(22801-59-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 22801-59-8(Hazardous Substances Data)

22801-59-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 22801-59-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,8,0 and 1 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 22801-59:
(7*2)+(6*2)+(5*8)+(4*0)+(3*1)+(2*5)+(1*9)=88
88 % 10 = 8
So 22801-59-8 is a valid CAS Registry Number.

22801-59-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(1,2-benzothiazol-3-yl)morpholine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:22801-59-8 SDS

22801-59-8Downstream Products

22801-59-8Relevant articles and documents

An Aryne-Based Route to Substituted Benzoisothiazoles

Chen, Yiding,Willis, Michael C.

, p. 4786 - 4789 (2015/10/12)

The combination of arynes, generated using fluoride from the corresponding 2-(trimethylsilyl)aryl triflates, and 3-hydroxy-4-aminothiadiazoles leads to the selective formation of 3-amino-substituted benzo[d]isothiazoles. Variation of the substitution pattern of the aryne precursor, and of the thiadiazole, is possible, with the target heterocycles being obtained in good to excellent yields. In all cases, use of 3-hydroxy-4-aminothiadiazoles leads to incorporation of the amino-substituent in the product heterocycle.

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