228088-38-8

Basic information

• Product Name: 3-(4-OXO-4H-CHROMEN-2-YL)BENZALDEHYDE
• Synonyms: 3-(4-OXO-4H-CHROMEN-2-YL)BENZALDEHYDE
• CAS NO: 228088-38-8
• Molecular Formula: C₁₆H₁₀O₃
• Molecular Weight: 250.25
• Mol File: 228088-38-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-OXO-4H-CHROMEN-2-YL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-OXO-4H-CHROMEN-2-YL)BENZALDEHYDE(228088-38-8)
• EPA Substance Registry System: 3-(4-OXO-4H-CHROMEN-2-YL)BENZALDEHYDE(228088-38-8)

Safety Data

• Hazardous Substances Data: 228088-38-8(Hazardous Substances Data)

Upstream product

• 228088-37-7 2-(3'-bromomethyl-phenyl)-4H-1-benzopyran-4-one 
• 84437-39-8 3'-Methylflavone 

Relevant articles and documents

Synthesis and biological activity of some new flavonyl-2,4-thiazolidinediones

A new series of flavonyl-2,4-thiazolidinediones (Va-c, VIa-c) was prepared by Knoevenagel reaction. The synthesized compounds were tested for their ability to inhibit rat kidney aldose reductase (AR) and for their insulinotropic activities in INS-1 cells.

Synthesis of some 4-[3' or 4'-(4 H-4-oxo-1-benzopyran-2-yl)phenyl]-1,4- dihydropyridine derivatives as potential calcium channel antagonists

In this study, the synthesis of new flavonoid derivatives, which possess a 1,4-dihydropyridine (1,4-DHP) moiety on the phenyl ring of flavone were realized. 3' or 4'-Formyl-flavones were synthesized, then the aldehyde groups of these compounds were converted to the 1,4-DHP moiety by the Hantzsch method. A series of 23 new derivatives having different substituents at C-3 and C-5 of the 1,4-DHP ring were prepared. Two compounds (8a, 8b) were tested for their calcium channel blocker activity and 8b exhibited the best result.