229309-19-7

Basic information

• Product Name: RALFINAMIDE
• CAS NO: 229309-19-7
• Molecular Formula: C₁₇H₁₉FN₂O₂
• Molecular Weight: 302.347
• Mol File: 229309-19-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: RALFINAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: RALFINAMIDE(229309-19-7)
• EPA Substance Registry System: RALFINAMIDE(229309-19-7)

Safety Data

• Hazardous Substances Data: 229309-19-7(Hazardous Substances Data)

Downstream Products

• 1160513-64-3 (R)-2-[4-(2-fluorobenzyloxy)benzylamino]propanamide methanesulfonate 

Relevant articles and documents

ALPHA-AMINOAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF PSYCHIATRIC DISORDERS

The disclosure relates to pharmacotherapy of a psychiatric disorder which is schizophrenia and/or anxiety, wherein schizophrenia includes schizophrenia related disorders such as brief psychotic disorders, delusional disorders, schizoaffective disorders, a

Alpha-aminoamide derivatives useful as antimigraine agents

α-Aminoamide derivatives useful as antimigraine agents, particularly for the treatment of head pain conditions such as migraine, cluster headache or other severe headache, are disclosed. The antimigraine agents of the invention are able to reduce or even stop the pain deriving from such conditions without, virtually, any side effects.

Alpha-aminoamide derivatives useful as analgesic agents

The present invention relates to novel and known alpha-aminoamide compounds, to a process for their preparation, to pharmaceutical composition containing them and to their use as therapeutic agents. In particular, the compounds of the present invention are endowed with analgesic properties and are particularly useful for the treatment and alleviation of chronic and neuropathic pain. Accordingly, one object of the present invention is to provide the use of a compound of formula (I) wherein: A is a —(CH2)m—, —(CH2)n—X— or —(CH2)v—O— group wherein m is an integer of 1 to 4, n is zero or an integer of 1 to 4, X is —S— or —NH—, and v is zero or an integer of 1 to 5; s is 1 or 2; R is a furyl, thienyl, or pyridyl ring or a phenyl ring optionally substituted by one or two substitutents independently chosen from halogen, cyano, C1-C4alkyl, C1-C4alkoxy and trifluoromethyl; R1is hydrogen or C1-C4alkyl; one of R2and R3is hydrogen and the other is hydrogen or C1-C4alkyl optionally substituted by hydroxy or phenyl; or R2and R3taken together with the carbon atom to which they are linked form a C3-C6cycloalkyl ring; or R2and R3are both methyl; R4is hydrogen or C1-C4alkyl.