23160-46-5

Basic information

• Product Name: 10-AMINO-1-DECANOL
• Synonyms: 10-AMINO-1-DECANOL;10-AMinodecanol;10-Aminodecan-1-ol
• CAS NO: 23160-46-5
• Molecular Formula: C₁₀H₂₃NO
• Molecular Weight: 173.3
• Product Categories: Miscellaneous Reagents;omega-Aminoalkanols;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Aliphatics;Amines
• Mol File: 23160-46-5.mol

Chemical Properties

• Melting Point: 72 °C
• Boiling Point: 154 °C / 3mmHg
• Flash Point: 116.4 °C
• Appearance: White solid
• Density: 0.889 g/cm³
• Vapor Pressure: 0.00101mmHg at 25°C
• Refractive Index: 1.46
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 15.20±0.10(Predicted)
• CAS DataBase Reference: 10-AMINO-1-DECANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 10-AMINO-1-DECANOL(23160-46-5)
• EPA Substance Registry System: 10-AMINO-1-DECANOL(23160-46-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 23160-46-5(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

InChI:InChI=1/C10H23NO/c11-9-7-5-3-1-2-4-6-8-10-12/h12H,1-11H2

Upstream product

• 112-47-0 1,10-Decanediol 

Downstream Products

• 16987-19-2 4-Amino-salicylsaeure-(10-amino-decylester) 
• 887353-29-9 1-[10-(2,3,4,6-O-tetrabenzoyl-β,D-glucopyranos-1-yl)-1-oxodecyl]-4,11-bis-(t-butoxycarbonylmethyl)-8-(10-(t-butoxycarbonylamino)decyl)-1,4,8,11-tetraazacyclotetradecane 
• 24566-82-3 10-bromodecylamine hydrobromide 

Relevant articles and documents

Parallel anti-sense two-step cascade for alcohol amination leading to ω-amino fatty acids and α,ω-diamines

Running two two-step cascades in parallel anti-sense to transform an alcohol to an amine allowed the conversion of ω-hydroxy fatty acids (ω-HFAs) and α,ω-diols to the corresponding ω-amino fatty acids (ω-AmFAs) and α,ω-diamines, respectively. The network required only two enzymes namely an aldehyde reductase (AHR) and a transaminase (TA). Benzylamine served on the one hand as amine donor and on the other hand after deamination to benzaldehyde also as oxidant. All ω-HFAs tested were efficiently transformed to their corresponding ω-AmFAs using purified enzymes as well as a whole-cell system, separately expressing both the enzymes, with conversions ranging from 80-95%. Additionally, a single-cell co-expressing all enzymes successfully produced the ω-AmFAs as well as the α,ω-diamines with >90% yield. This system was extended by employing a lactonase, enabling the transformation of ?-caprolactone to its corresponding ω-AmFA with >80% conversion.

The preparation obtained by homogeneous catalysis mellow amination method of the primary amine

The invention relates to a method for producing primary amines comprising at least one functional group of formula (-CH2-NH2), by alcohol amination of educts which comprise at least one functional group of formula (-CH2-OH), using ammonia, and elimination of water. The homogeneously catalyzed alcohol amination is carried out in the presence of at least one complex catalyst which contains at least one element selected from the groups 8 and 9 of the periodic table and at least one phosphorus donor ligand of general formula (I).

METHOD FOR PRODUCING ALKANOL AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION

PROBLEM TO BE SOLVED: To provide a method for producing alkanol amines by alcohol amination of diols using ammonia under elimination of water. SOLUTION: The invention relates to a method for producing alkanol amines which comprise a primary amino group (-NH2) and a hydroxyl group (-OH), by alcohol amination of diols comprising two hydroxyl groups (-OH) using ammonia under elimination of water. The reaction is homogeneously catalyzed in the presence of at least one complex catalyst which contains at least one element selected from groups 8, 9 and 10 of the periodic table and at least one donor ligand. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPO&INPIT

PROCESS FOR PREPARING DI-, TRI- AND POLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION

Process for preparing primary amines which have at least one functional group of the formula (—CH2—NH2) and at least one further primary amino group by alcohol amination of starting materials having at least one functional group of the formula (—CH2—OH) and at least one further functional group (—X), where (—X) is selected from among hydroxyl groups and primary amino groups, by means of ammonia with elimination of water, wherein the reaction is carried out homogeneously catalyzed in the presence of at least one complex catalyst comprising at least one element selected from groups 8, 9 and 10 of the Periodic Table and also at least one donor ligand.

PROCESS FOR PREPARING ALKANOLAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION

Process for preparing alkanolamines which have a primary amino group (—NH2) and a hydroxyl group (—OH) by alcohol amination of diols having two hydroxyl groups (—OH) by means of ammonia with elimination of water, wherein the reaction is carried out homogeneously catalyzed in the presence of at least one complex catalyst comprising at least one element selected from groups 8, 9 and 10 of the Periodic Table and also at least one donor ligand.

PROCESS FOR THE PREPARATION OF PRIMARY AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION

Process for the preparation of primary amines which have at least one functional group of the formula (—CH2—NH2) by alcohol amination of starting materials which have at least one functional group of the formula (—CH2—OH), with ammonia, with the elimination of water, where the alcohol amination is carried out under homogeneous catalysis in the presence of at least one complex catalyst which comprises at least one element selected from groups 8 and 9 of the Periodic Table of the Elements, and also at least one phosphorus donor ligand of the general formula (I).

Redox self-sufficient biocatalyst network for the amination of primary alcohols

Driving the machinery: A biocatalytic redox-neutral cascade for the preparation of terminal primary amines from primary alcohols at the expense of ammonia has been established in a one-pot one-step method (see picture). Applying this artificial biocatalyst network, long-chain 1,ω-alkanediols were converted into diamines, which are building blocks for polymers, in up to 99 % conversion. Copyright