- Benzofuran derivatives useful as inhibitors of mammalian leukotriene biosynthesis
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Benzofuran derivatives, pharmaceutical compositions and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic condit
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- Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis
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Compounds of the Formula I: STR1 and pharmaceutically acceptable salts thereof are inhibitors of leukotriene biosynthesis. These compounds inhibit the mammalian 5-lipoxygenase enzyme, thus preventing the metabolism of arachidonic acid to the leukotrienes.
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- Benzopyran-2-carboxylic acids in the prevention of asthmatic symptoms
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There are described certain mono-chromone-2-carboxylic acids of formula, SPC1 Having one substituent in the 5 or 6 position or having 2 or more substituents in the 5,6,7 or 8 positions. There are also described processes for making the compounds and pharmacetuical compositions, for the treatment of asthma, containing the compounds.
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