cas 23234-43-7, D-TYROSINE ETHYL ESTER HYDROCHLORIDE

A series of 2-chloro-3-(4-alkoxyphenyl)propionic acids containing a quarternary carbon atom in the alkoxy moiety was prepared and the hypolipidemic and hypoglycemic activities were evaluated. Of the 18 compounds synthesized, ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropyloxy)phenyl]propionate was the best with respect to biological activity and toxicity. Its functional derivatives and optically resolved enantiomers were also prepared. Structure-activity relationships are discussed briefly.

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23234-43-7

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Chemical Properties

Appearance/Colour :white crystalline powder

Boiling Point: 373.5 °C at 760 mmHg

Flash Point:179.7 °C

Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Vapor Pressure: 4.14E-06mmHg at 25°C

PSA: 72.55000

LogP: 2.32740

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