- HEPATITIS B ANTIVIRAL AGENTS
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The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.
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Page/Page column 214
(2013/07/05)
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- TREATMENT OF METABOLIC SYNDROME WITH PIPERIDINE AMIDES
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The present invention relates to piperidine derivatives of formula (I) and (II), their pharmaceutical compositions and methods of treatment of metabolic syndrome disorders such as obesity, diabetes, hypertension and hyperlipidemia using the said compounds
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- INDOLE DERIVATIVE AND USE FOR TREATMENT OF CANCER
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The present invention relates to a compound represented by the formula (I’) wherein A is a benzene ring optionally having substituents, R1, R2a and R3 are each a hydrogen atom, a hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, R1 and R2a may form a ring via X, when R1 and R2a form a ring via X, R1 and R2a are each a bond or a divalent C1-5 acyclic hydrocarbon group optionally having substituents, and X is a bond, an oxygen atom, an optionally oxidized sulfur atom or an imino group optionally having a substituent, provided that R1, R2a and X are not bonds at the same time, or a salt thereof, and an agent for inhibiting kinase (phosphorylation enzyme), which contains this compound or a prodrug thereof. The compound of the present invention has an inhibitory activity against kinase such as a vascular endothelial growth factor receptor (VEGFR) and the like, and is useful as an agent for the prophylaxis or threatment of cancer and the like.
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Page/Page column 256-257
(2010/02/15)
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