Construction of the diene moiety (C9-C18) of amphidinolide B, a 26- membered macrolide
The diene moiety (C9-C18) of amphidinolide B, a potent cytotoxic macrolide isolated from the marine dinoflagellate Amphidinium sp., has been synthesized by a coupling reaction of an alkynyl anion of 5 and the aldehyde 7, followed by Michael addition and methylenation.
Ohi, Katsuhide,Nishiyama, Shigeru
p. 571 - 572
(2007/10/03)
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