Method for protection from AZT side effects and toxicity
S-ω(ω-aminoalkylamino)alkyl dihydrogen phosphorothioates or pharmaceutically acceptable derivatives thereof are useful in protecting a patient undergoing AZT treatment for AIDS and AIDS-related complex from the harmful side effects or reactions and toxici
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(2008/06/13)
Radioprotective effect of low doses of 2-(1-naphthylmethyl)-2-imidazoline alone or associated with phosphorothioates
In the mouse, the intraperitoneal injection of 2-(1-naphthylmethyl)-2-imidazoline has a radioprotective effect even at low doses.Its association with S- phosphorothioate (WR 2721) or S-phosphorothioate (WR 151327) at low doses led to an ethancement of their respective radioprotective activities without any apparent side effects.These results strengthen the interest of this non-sulphur compound as a radioprotector. radioprotective compounds/phosphorothioates/WR 2721/WR 151327/imidazoline/associations
Laval, J. D.,Roman, V.,Laduranty, J.,Miginiac, L.,Lion, C.,et al.
p. 709 - 714
(2007/10/02)
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