Facile Synthesis of (=/-)-Isolongifolene and (+/-)-Isolongifolenedione Involving Ar1-5 Cyclisations
Facile syntheses of (+/-)-isolongifolene 2 and (+/-)-isolongifolenedione 20 have been accomplished utilising aryl participated cyclisations of the bromophenol 15 and the diazoketone 11 respectively as the key steps.
Cobalt-catalyzed oxidation of terpenes: Co-MCM-41 as an efficient shape-selective heterogeneous catalyst for aerobic oxidation of isolongifolene under solvent-free conditions
Cobalt-containing MCM-41 was used as a heterogeneous catalyst for the liquid-phase aerobic oxidation of isolongifolene, one of the most available sesquiterpenes. The material was prepared by direct incorporation of cobalt into the framework through the hy
Robles-Dutenhefner, Patricia A.,da Silva Rocha, Kelly A.,Sousa, Edesia M.B.,Gusevskaya, Elena V.
experimental part
p. 72 - 79
(2009/09/25)
Aryl participated cyclisations involving indane derivatives a total synthesis of (±)-isolongifolene
A total synthesis of (±)-isolongifolene (1) has been accomplished using intramolecular anionic cyclisation of the bromophenol 2 as the key step. Aryl participated intramolecular cyclisation of the diamethyl ketones 17 and 23 provided the dienediones 18 and 24 which were stereoselectively converted into the diketones 19 and 25 respectively.