Silver-catalyzed decarboxylative homocoupling reaction for the construction of tetrafluoroethylene-bridging aromatic compounds
The Ag(I)-catalyzed decarboxylative homocoupling from the difluoroacetate has been developed to the synthesis of symmetric CF2–CF2 containing dimers. This radical dimerization overpasses the prefunctionalization of the substrate and provides a direct and efficient method for construction of tetrafluoroethylene bridge-linked homodimers.
Under suitable conditions elemental fluorine can be added across the carbon-carbon triple bond of arylacetylenes forming tetrafluoroethane derivatives - ArCF2CF2R - in good yields.
Gatenyo, Julia,Rozen, Shlomo
experimental part
p. 332 - 335
(2009/12/03)
Direct nucleophilic fluorination of carbonyl groups of benzophenones and benzils with Deoxofluor
The carbonyl groups of diaryl ketones and diaryl diketones were directly fluorinated with bis(2-methoxyethyl)aminosulfur trifluoride (Deoxofluor) under neat conditions to give the corresponding gem-difluorides and tetrafluorinated derivatives in moderate