- Preparation method and medical application of unsaturated cyclic amine pyridine disulfide derivative
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The invention relates to the field of medicinal chemistry, in particular to a series of unsaturated cyclic amine pyridine disulfide derivatives, and further discloses a preparation method and medical application of the compounds. The invention discloses a novel unsaturated cyclic amine pyridine disulfide derivative and a preparation method and application thereof for the first time, especially for treating atherosclerotic diseases, myocardial infarction, stroke, peripheral arterial diseases, acute coronary syndromes and thrombosis in an anti-angiogenesis operation period.
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Paragraph 0108-0112
(2021/05/19)
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- Preparation method and medical application of unsaturated cyclic amine cysteine disulfide derivative
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The invention relates to the field of medicinal chemistry, in particular to a series of unsaturated cyclic amine cysteine disulfide derivatives, and further discloses a preparation method and medical application of the compounds. The compound is particularly used for treating atherosclerotic diseases, myocardial infarction, stroke, peripheral arterial diseases, acute coronary syndromes and thrombosis during anti-angiogenesis surgery.
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Paragraph 0123-0127
(2021/05/29)
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- Unsaturated cyclic amine disulfide derivative, preparation method and medical application thereof (by machine translation)
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Compared with clopidogrel, the compound has better metabolic characteristics, can bypass P450 systems in the human body, and has good drug-forming property. The invention further discloses a preparation method of the compound and an application of the com
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Paragraph 0081-0084
(2020/07/15)
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- Clopidogrel metabolic active body disulfide derivativeS as well as preparation method and medical application thereof
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The invention relates to the field of medicinal chemistry, and provides a series of clopidogrel metabolic active body disulfide derivatives, pharmaceutically acceptable salts or solvates. Compared with clopidogrel, the compounds have better metabolic characteristics, can bypass a P450 system in a human body, and have good druggability. The invention also discloses a preparation method of the compounds and application of the compounds in the field of medicines, especially in the field of medicines for treating cardiovascular and cerebrovascular thrombosis or embolic diseases.
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Paragraph 0158-0161
(2020/08/18)
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- Cyclic amino compounds
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A cyclic amino compound represented by the following formula: or a pharmacologically acceptable salt thereof. R1is a substitutable phenyl group. R2is a substitutable aliphatic acyl group, a substitutable benzoyl group or an alkoxycar
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