239482-98-5

Basic information

• Product Name: 2-(AMINOETHYL)-1-N-BOC-PIPERIDINE
• Synonyms: 2-(AMINOETHYL)-1-N-BOC-PIPERIDINE;2-(AMINOETHYL)-1-BOC-PIPERIDINE;2-(2-AMINO-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;2-(2-AMINOETHYL)-1-BOC-PIPERIDINE;CHEMBRDG-BB 4004161;1-Boc-2-(aminoethyl)piperidine;2-(boc-aminoethyl)piperidine;4-aminoethyl-n-boc-piperidine
• CAS NO: 239482-98-5
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 228.33
• Product Categories: pharmacetical;Piperidines;Heterocycle-Pyridine series
• Mol File: 239482-98-5.mol

Chemical Properties

• Boiling Point: 316 °C at 760 mmHg
• Flash Point: 144.9 °C
• Appearance: /
• Density: 1.01 g/cm³
• Vapor Pressure: 0.000422mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.56±0.10(Predicted)
• CAS DataBase Reference: 2-(AMINOETHYL)-1-N-BOC-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(AMINOETHYL)-1-N-BOC-PIPERIDINE(239482-98-5)
• EPA Substance Registry System: 2-(AMINOETHYL)-1-N-BOC-PIPERIDINE(239482-98-5)

Safety Data

• Hazard Codes: Xn,N
• Statements: 36/37/38-50-22
• Safety Statements: 26-36/37/39-61
• Hazardous Substances Data: 239482-98-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2-(AMINOETHYL)-1-N-BOC-PIPERIDINE is used as a research chemical for the development of novel pharmaceutical compounds. Its unique structure and properties make it a valuable building block in the synthesis of various drugs, particularly those targeting the central nervous system.
Used in Chemical Synthesis:
In the chemical synthesis industry, 2-(AMINOETHYL)-1-N-BOC-PIPERIDINE is used as a versatile intermediate for the creation of a wide range of chemical products. Its Boc-protected structure allows for selective reactions, making it a useful component in the synthesis of complex organic molecules.
Used in Drug Delivery Systems:
Similar to gallotannin, 2-(AMINOETHYL)-1-N-BOC-PIPERIDINE can also be employed in the development of drug delivery systems. Its compatibility with various organic and metallic nanoparticles makes it a promising candidate for improving the delivery, bioavailability, and therapeutic outcomes of certain drugs.

InChI:InChI=1/C12H24N2O2/c1-12(2,3)16-11(15)14-9-5-4-6-10(14)7-8-13/h10H,4-9,13H2,1-3H3/p+1/t10-/m1/s1

Upstream product

• 741287-29-6 2-(2-Azidoethyl)piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 672326-14-6 2-{[3-bromo-5-(2-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-ylamino]ethyl}piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

HISTAMINE H3 RECEPTOR LIGANDS

Compounds of formula (I) (and pharmaceutically acceptable salts thereof) are histamine H3 receptor ligands. A in the formula represents (CH2)m, m being from 1 to 3; B is (CH2)n, n being from 1 to 3; x is from 0 to 2; Ris C1 to C10 hydrocarbyl, in which up to 2 carbon atoms may be replaced by O, S or N; and up to 2 hydrogen atoms may be replaced by halogen; Ris H or C1 to C15 hydrocarbyl, in which up to 3 carbon atoms may be replaced by O, S or N, and up to 3 hydrogen atoms may be replaced by halogen; Ris absent when -Y-Z-R2 is attached to W, or is H or C1 to C7 hydrocarbyl when -Y-Z-Ris not attached to W; W is nitrogen; X is -CH2-, -O- or -NR-, Rbeing H or C1 to C3 alkyl; Y replaces a hydrogen atom on any of A, B, W and X, and is C2 to C10 alkylene, in which one non-terminal carbon atom may be replaced by O; and Z is (II), (III), (IV), (V), (VI), or (VII) wherein R, Rand Rare independently H or C1 to C15 hydrocarbyl, in which up to 3 carbon atoms may be replaced by O or N, and up to 3 hydrogen atoms may be replaced by halogen, and Q is H or methyl, or Q is linked to Ror Rto form a five-membered ring or Q is linked to Rto form a six-membered ring

1H-imidazopyridine derivatives

1H-Imidazopyridine derivatives represented by the following general formula or salts thereof: wherein R1represents hydrogen atom, hydroxyl group, an alkyl group, a cycloalkyl group, styryl group, or an aryl group; R2represents hydrog