- Synthesis of sultam derivatives with expected biological activity. 15
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4-(Trihydro-2H-1,2-thiazole-1,1-dioxide-2-yl)benzophenone (1), 4-(3,5-dimethyl-1′,2′-thiazine-1′,1′-dioxide-2-yl) benzophenone (2), and 4-(tetrahydro-2H-1,2-thiazine-1,1-dioxide-2-yl) benzophenone (6) were obtained from 4-aminobenzophenone and the appropriate reagents. Isomeric (E-) and (Z-) 2-Ethoxycarbonyl-4-phenyl-4-(4-tetrahydro-1,2- thiazine-1,1-dioxide-2-yl)phenyl-3-butenoic acids (11 and 12) and 2-carboxy-4(N-phenyl-thiocarbamoyl)-1-phenyl-6-(tetrahydro-2H-1,2-thiazine-1, 1-dioxide-2-yl)naphthalene (16) were also synthesized.
- Doss,Baghos,Abdelhamid,Halim
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p. 816 - 825
(2007/10/03)
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