- Sulfonic acid sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds
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The compounds of formula I herein exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More specifically, they are inhibitors of the activity of Factor Xa. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, and their use, for treating a patient suffering from, or subject to, a physiological condition which can be ameliorated by the administration of an inhibitor of the activity of Factor Xa.
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- Synthesis and Evaluation of Ureido- and Vinylureidopenicillins as Inhibitors of Intraruminal Lactic Acid Production
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A series of 14 vinylureidopenicillins and a series of 9 ureidopenicillins were prepared by reaction of 6-aminopenicillanic acid with vinyl isocyanates and isocyanates.These compounds were evaluated for their potential to protect ruminants against lactic a
- Clark, Robin D.,Caroon, Joan M.,Harrison, Ian T.,Kluge, Arthur F.,Unger, Stefan H.,et al.
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p. 1250 - 1253
(2007/10/02)
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