243455-57-4

Basic information

• Product Name: 5-(3-BROMOPHENYL)-1,3-OXAZOLE
• Synonyms: 5-(3-BROMOPHENYL)-1,3-OXAZOLE;5-(3-Brom-phenyl)-oxazole;5-(3-Bromophenyl)-1,3-oxazole 97%;5-(3-Bromo-phenyl)-oxazole;5-(3-Bromophenyl)-1,3-oxazole97%
• CAS NO: 243455-57-4
• Molecular Formula: C9H6BrNO
• Molecular Weight: 224.05
• Product Categories: Heterocycles
• Mol File: 243455-57-4.mol

Chemical Properties

• Melting Point: 57-61
• Boiling Point: 303.9 °C at 760 mmHg
• Flash Point: 137.6 °C
• Appearance: /
• Density: 1.524 g/cm³
• Vapor Pressure: 0.00163mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 5-(3-BROMOPHENYL)-1,3-OXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-BROMOPHENYL)-1,3-OXAZOLE(243455-57-4)
• EPA Substance Registry System: 5-(3-BROMOPHENYL)-1,3-OXAZOLE(243455-57-4)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 243455-57-4(Hazardous Substances Data)

Usage

Uses

Used in Research and Development:
5-(3-BROMOPHENYL)-1,3-OXAZOLE is used as a starting material or an intermediate in organic synthesis for various research and development purposes. Its unique molecular structure and stability make it a valuable component in the synthesis of new organic compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 5-(3-BROMOPHENYL)-1,3-OXAZOLE is utilized as a key building block for the creation of complex organic molecules. Its presence of a bromine atom allows for further functionalization and modification of the molecule, enabling the development of novel compounds with potential applications in various industries.

InChI:InChI=1/C9H6BrNO/c10-8-3-1-2-7(4-8)9-5-11-6-12-9/h1-6H

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 

Relevant articles and documents

Libraries of C-5 Substituted Imidazoles and Oxazoles by Sequential Van Leusen (VL)–Suzuki, VL–Heck and VL–Sonogashira in Imidazolium-ILs with Piperidine-Appended-IL as Base

Facile access to diverse C5-substituted imidazoles and oxazoles via sequential Van Leusen–Suzuki, Van Leusen–Heck, and Van Leusen–Sonogashira protocols, employing imidazolium-ILs as solvents along with piperidine-appended imidazolium [PAIM][NTf2/sub

OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT)

The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, A, Q, W and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.

BIARYL SUBSTITUTED THIAZOLES, OXAZOLES AND IMIDAZOLES AS SODIUM CHANNEL BLOCKERS

Biaryl substituted thiazole, oxazole and imidazole compounds are sodium channel blockers useful for the treatment of pain. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more

A solid-phase equivalent of van Leusen's TosMIC, and its application in oxazole synthesis

Polystyrene-SH resin, prepared from Merrifield resin in two steps, was converted to polystyrene-SO2-CH2-NC in three steps. This resin functions as a solid-phase equivalent of p-tolylsulfonylmethyl isocyanide (TosMIC). Thus, reaction with aromatic aldehydes and tetrabutylammonium hydroxide as base yields 5-aryloxazoles.