243972-26-1

Basic information

• Product Name: 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected
• Synonyms: 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected;[5-(TRIBUTYLSTANNYL)THIAZOL-2-YL]CARBAMIC ACID TERT-BUTYL ESTER;2-Amino-5-(tributylstannyl)-1,3-thiazole, 2-BOC protected;{2-[(tert-Butoxycarbonyl)amino]-1,3-thiazol-5-yl}tributylstannane, tert-Butyl [5-(tributylstannyl)-1,3-thiazol-2-yl]carbamate;2-AMino-5-(tributylstannyl)-1,3-thiazole;2-(N-Boc-amino)-5-(tributylstannyl)thiazole
• CAS NO: 243972-26-1
• Molecular Formula: C₂₀H₃₈N₂O₂SSn
• Molecular Weight: 489.29
• Product Categories: Stannanes;organic tin
• Mol File: 243972-26-1.mol

Chemical Properties

• Melting Point: 78-86°C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.24±0.70(Predicted)
• CAS DataBase Reference: 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected(243972-26-1)
• EPA Substance Registry System: 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected(243972-26-1)

Safety Data

• Hazard Codes: T,N
• Statements: 21-25-36/38-48/23/25-50/53
• Safety Statements: 36/37/39-45-60-61
• RIDADR: UN 3146 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 243972-26-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected is used as a building block for the synthesis of complex organic molecules. Its tributylstannyl group facilitates selective reactions with other organic compounds, while the N-BOC protection ensures the stability of the amino group during these reactions, making it a valuable tool for creating diverse chemical structures in the laboratory.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected is utilized as a key intermediate in the development of new drugs. Its unique structure and reactivity allow for the creation of novel therapeutic agents with potential applications in various medical fields.
Used in Chemical Research:
2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected is employed as a research tool in chemical studies. Its properties and reactivity are investigated to understand the underlying mechanisms of various chemical reactions and to explore new synthetic pathways for the production of innovative compounds.
Used in Material Science:
In the field of material science, 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected is used for the development of new materials with unique properties. Its incorporation into polymers, for instance, can lead to materials with enhanced characteristics, such as improved stability, reactivity, or selectivity.
Overall, 2-Amino-5-(tributylstannyl)-1,3-thiazole, N-BOC protected is a multifaceted chemical compound with a wide range of applications across various industries, including organic synthesis, pharmaceuticals, chemical research, and material science. Its unique structure and reactivity make it an indispensable tool for the creation of innovative and complex chemical structures.

InChI:InChI=1/C8H11N2O2S.3C4H9.Sn/c1-8(2,3)12-7(11)10-6-9-4-5-13-6;3*1-3-4-2;/h4H,1-3H3,(H,9,10,11);3*1,3-4H2,2H3;/rC20H38N2O2SSn/c1-7-10-13-26(14-11-8-2,15-12-9-3)17-16-21-18(25-17)22-19(23)24-20(4,5)6/h16H,7-15H2,1-6H3,(H,21,22,23)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1461-22-9 tributyltin chloride 
• 170961-15-6 tert-butyl 1,3-thiazole-2-yl-carbamate 

Downstream Products

• 1542268-01-8 C₂₇H₂₈N₆O₄S₂ 
• 1542268-21-2 C₂₅H₃₀FN₇O₅S 
• 1542268-02-9 C₂₇H₂₈N₆O₆S₂ 
• 1542268-03-0 C₂₅H₃₁N₇O₅S 
• 1542268-37-0 C₂₅H₃₁N₇O₅S 
• 1391926-40-1 tert-butyl (5-(4-(4-(dimethylcarbamoyl)phenoxy)-6-morpholino-1,3,5-triazin-2-yl)thiazol-2-yl)carbamate 

Relevant articles and documents

NOVEL TRIAZINE COMPOUNDS

The present invention relates to novel triazine compounds of formula (1). The present invention also discloses compounds of formula I along with other pharmaceutical ac-ceptable excipients and use of the compounds to modulate the PI3K/ mTOR pathway

NOVEL TRIAZINE COMPOUNDS

The present invention relates to novel triazine compounds of formula (1), methods of their preparation, pharmaceutical compositions containing these compounds and the use of these compounds to treat proliferative disorders such as tumors and cancers and also other conditions and disorders related to or associated with dysregulation of PI3 Kinases, PI3 Kinase pathway, mTOR and/ or the mTOR pathway.

FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE

The invention relates to thiazole compounds of Formula (I) and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.

Thiazole compounds and methods of use

The invention relates to thiazole compounds of Formula I and Formula II and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.

Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.