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2-Hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid, also known as Vanillactic acid, is a naturally occurring metabolite of dihydroxyphenylalanine (DOPA), which is an isomer of the immediate precursor of dopamine. It is characterized by the presence of hydroxy and methoxy groups on its phenyl ring, as well as a carboxylic acid group, which may contribute to its potential applications in various fields.

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  • 2475-56-1 Structure
  • Basic information

    1. Product Name: 2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid
    2. Synonyms: 2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid;Vanillactic acid;3-Methoxy-4-hydroxyphenyllactic acid;3-(4-Hydroxy-3-methoxyphenyl)-2-hydroxypropanoic acid;α,4-Dihydroxy-3-methoxybenzenepropionic acid;2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)propionic acid;Benzenepropanoic acid, a,4-dihydroxy-3-Methoxy-;SVYIZYRTOYHQRE-UHFFFAOYSA-N
    3. CAS NO:2475-56-1
    4. Molecular Formula: C10H12O5
    5. Molecular Weight: 212.2
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2475-56-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 432.6°Cat760mmHg
    3. Flash Point: 174.4°C
    4. Appearance: /
    5. Density: 1.38g/cm3
    6. Vapor Pressure: 2.99E-08mmHg at 25°C
    7. Refractive Index: 1.592
    8. Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
    9. Solubility: Methanol (Slightly), Water (Slightly)
    10. PKA: 3.80±0.10(Predicted)
    11. Stability: Hygroscopic
    12. CAS DataBase Reference: 2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid(CAS DataBase Reference)
    13. NIST Chemistry Reference: 2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid(2475-56-1)
    14. EPA Substance Registry System: 2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid(2475-56-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2475-56-1(Hazardous Substances Data)

2475-56-1 Usage

Uses

Used in Pharmaceutical Industry:
2-Hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid is used as a pharmaceutical compound for its potential therapeutic effects. As a metabolite of DOPA, it may have implications in the treatment of neurological disorders related to dopamine imbalances, such as Parkinson's disease. Its unique structure with hydroxy and methoxy groups may also contribute to its interactions with biological targets, making it a promising candidate for drug development.
Used in Nutraceutical Industry:
In the nutraceutical industry, 2-hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid may be used as a dietary supplement or functional ingredient due to its potential health benefits. Its role as a metabolite of DOPA suggests that it could have a positive impact on cognitive function and mood regulation, making it a valuable addition to nutraceutical products aimed at supporting brain health.
Used in Cosmetic Industry:
2-Hydroxy-3-(4-hydroxy-3-methoxy-phenyl)-propanoic acid may also find applications in the cosmetic industry, where its unique chemical structure could be utilized for its potential antioxidant, anti-inflammatory, or skin-whitening properties. Its presence in natural sources and potential health benefits may make it an attractive ingredient for cosmetic products that promote skin health and beauty.

Check Digit Verification of cas no

The CAS Registry Mumber 2475-56-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,7 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2475-56:
(6*2)+(5*4)+(4*7)+(3*5)+(2*5)+(1*6)=91
91 % 10 = 1
So 2475-56-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O5/c1-15-9-5-6(2-3-7(9)11)4-8(12)10(13)14/h2-3,5,8,11-12H,4H2,1H3,(H,13,14)

2475-56-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

1.2 Other means of identification

Product number -
Other names Vanillyllactate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2475-56-1 SDS

2475-56-1Downstream Products

2475-56-1Relevant articles and documents

Conversion of dehydrodiferulic acids by human intestinal microbiota

Braune, Annett,Bunzel, Mirko,Yonekura, Reiko,Blaut, Michael

experimental part, p. 3356 - 3362 (2010/06/16)

Plant cell wall associated dehydrodiferulic acids (DFA) are abundant components of cereal insoluble dietary fibers ingested by humans. The ability of human intestinal microbiota to convert DFA was studied in vitro by incubating 8-O-4- and 5-5-coupled DFA with fecal suspensions. 8-O-4-DFA was completely degraded by the intestinal microbiota of the majority of donors, yielding homovanillic acid, 3-(3,4-dihydroxyphenyl)propionic acid, and 3,4-dihydroxyphenylacetic acid as the main metabolites. The transient formation of ferulic acid and presumably 3-(3-hydroxy-4-methoxyphenyl)pyruvic acid suggests an initial cleavage of the ether bond. In contrast to 8-O-4-DFA, the 5-5-coupled DFA was not cleaved into monomers by any of the fecal suspensions. Only the side chains were hydrogenated and the methoxy groups were demethylated. The cleavage of DFA by human intestinal microbiota, which depended on their coupling type, may affect both the bioavailability of DFA and the degradability of DFA-coupled fiber in the gut.

A modified synthesis of (±)-β-aryllactic acids

Wong,Xu,Chang,Lee

, p. 793 - 797 (2007/10/02)

The synthesis of racemic forms of the reportedly active principle of Danshen, namely (±)-β-(3,4-dihydroxyphenyl)lactic acid [(±)3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid] and its seven racemic derivatives is reported.

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