247564-59-6

Basic information

• Product Name: 5,7-DIFLUORO-1,3-DIHYDRO-2H-INDOL-2-ONE
• Synonyms: 5,7-Difluoro-1,3-dihydro-2H-indol-2-one, 5,7-Difluoroindolin-2-one;5,7-Difluoro-2-oxindole;5,7-Difluoro-2-oxyindole;5,7-Difluoroindolin-2-one
• CAS NO: 247564-59-6
• Molecular Formula: C8H5F2NO
• Molecular Weight: 169.13
• Mol File: 247564-59-6.mol

Chemical Properties

• Melting Point: 219～222℃
• Boiling Point: 284.0±40.0 °C(Predicted)
• Appearance: /
• Density: 1.415±0.06 g/cm3(Predicted)
• PKA: 11.66±0.20(Predicted)
• CAS DataBase Reference: 5,7-DIFLUORO-1,3-DIHYDRO-2H-INDOL-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-DIFLUORO-1,3-DIHYDRO-2H-INDOL-2-ONE(247564-59-6)
• EPA Substance Registry System: 5,7-DIFLUORO-1,3-DIHYDRO-2H-INDOL-2-ONE(247564-59-6)

Safety Data

• Hazardous Substances Data: 247564-59-6(Hazardous Substances Data)

Usage

Uses

Due to the limited information available about 5,7-difluoro-1,3-dihydro-2H-indol-2-one, its applications are not well-documented. However, based on its classification as an indolone, it can be inferred that it may have potential uses in various industries, such as pharmaceuticals, materials science, or chemical research. Further research and development would be required to explore and confirm its potential applications.

Relevant articles and documents

Process for Preparing Substituted 1,3-dihydro-2H-indol-2-ones

Process for preparing 1,3-dihydro-2H-indol-2-ones, starting from thioalkyl-, or thiocycloalkyl-substituted indol-2-one compounds, involving a) dissolving or suspending the thioalkyl-, or thiocycloalkyl-substituted indol-2-one compounds in a polar solvent, b) adding a sulfur-containing salt to the solution or suspension, and c) heating the reaction mixture under reflux at a temperature which corresponds at most to the boiling temperature of the solvent. Use of the inventively prepared 1,3-dihydro-2H-indol-2-one as intermediates for the synthesis of fine chemicals and active ingredients from pharmacy and/or agriculture.

Phenylaminopropanol derivatives and methods of their use

The present invention is directed to phenylaminopropanol derivatives of formulae I, II, and III: [image] or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, schizophrenia, and combinations thereof.