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CAS

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247571-59-1

5-ALLYL-3-MERCAPTOINDOLO[2,3-E]-1,2,4-TRIAZINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 247571-59-1 Structure

  • Basic information

    1. Product Name: 5-ALLYL-3-MERCAPTOINDOLO[2,3-E]-1,2,4-TRIAZINE
    2. Synonyms: 5-ALLYL-3-MERCAPTO-5H-1,2,4-TRIAZINO[5,6-B]INDOLE;5-ALLYL-3-MERCAPTOINDOLO[2,3-E]-1,2,4-TRIAZINE;9-ALLYL-9H-1,3,4,9-TETRAAZA-FLUORENE-2-THIOL;TIMTEC-BB SBB001623;5-Allyl-5H-[1,2,4]triazino[5,6-b]indole-3-thiol;1,2,4-Triazino[5,6-b]indole-3-thiol, 5-allyl-;5-allyl-2H-[1,2,4]triazino[5,6-b]indole-3-thione;5-prop-2-enyl-2H-[1,2,4]triazino[5,6-b]indole-3-thione
    3. CAS NO:247571-59-1
    4. Molecular Formula: C12H10N4S
    5. Molecular Weight: 242.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 247571-59-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-ALLYL-3-MERCAPTOINDOLO[2,3-E]-1,2,4-TRIAZINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-ALLYL-3-MERCAPTOINDOLO[2,3-E]-1,2,4-TRIAZINE(247571-59-1)
    11. EPA Substance Registry System: 5-ALLYL-3-MERCAPTOINDOLO[2,3-E]-1,2,4-TRIAZINE(247571-59-1)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 247571-59-1(Hazardous Substances Data)

247571-59-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 247571-59-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,7,5,7 and 1 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 247571-59:
(8*2)+(7*4)+(6*7)+(5*5)+(4*7)+(3*1)+(2*5)+(1*9)=161
161 % 10 = 1
So 247571-59-1 is a valid CAS Registry Number.

247571-59-1Downstream Products

247571-59-1Relevant articles and documents

Design, synthesis, and biological evaluation of 1,2,3-triazole-linked triazino[5,6-b]indole-benzene sulfonamide conjugates as potent carbonic anhydrase I, II, IX, and XIII inhibitors

Angeli, Andrea,Arifuddin, Mohammed,Biswas, Rashmita,Chinchilli, Krishna Kartheek,Korra, Laxman Naik,Supuran, Claudiu T.,Thacker, Pavitra S.

, (2020/06/17)

A series of 1,2,3-triazole-linked triazino[5,6-b]indole-benzene sulfonamide hybrids (6a– 6o) was synthesized and evaluated for carbonic anhydrase (CA, EC 4.2.1.1) inhibitory activity against the human (h) isoforms hCA I, II, XIII (cytosolic isoforms), and hCA IX (transmembrane tumor-associated isoform). The results revealed that the compounds 6a–6o exhibited Ki values in the low to medium nanomolar range against hCA II and hCA IX (Kis ranging from 7.7 nM to 41.3 nM) and higher Ki values against hCA I and hCA XIII. Compound 6i showed potent inhibition of hCA II (Ki = 7.7nM), being more effective compared to the standard inhibitor acetazolamide (AAZ) (Ki = 12.1 nM). Compounds 6b and 6d showed moderate activity against hCA XIII (Ki= 69.8 and 65.8 nM). Hence, compound 6i could be consider as potential lead candidate for the design of potent and selective hCA II inhibitors.

Triazino indole-quinoline hybrid: A novel approach to antileishmanial agents

Sharma, Rashmi,Pandey, Anand Kumar,Shivahare, Rahul,Srivastava, Khushboo,Gupta, Suman,Chauhan, Prem M.S.

, p. 298 - 301 (2015/06/01)

A novel series of 1,2,4-triazino-[5,6b]indole-3-thione covalently linked to 7-chloro-4-aminoquinoline have been synthesized and evaluated for their in vitro activity against extracellular promastigote and intracellular amastigote form of Leishmania donovani. Among all tested compounds, compounds 7a and 7b were found to be the most active with IC50 values 1.11, 0.36 μM and selectivity index (SI) values 67, >1111, respectively, against amastigote form of L. donovani which is several folds more potent than the standard drugs, miltefosine (IC50 = 8.10 μM, SI = 7) and sodium stibo-gluconate (IC50 = 54.60 μM, SI ≥ 7).

Triazino indole-quinoline hybrid: A novel approach to antileishmanial agents

Sharma, Rashmi,Pandey, Anand Kumar,Shivahare, Rahul,Srivastava, Khushboo,Gupta, Suman,Chauhan, Prem M.S.

, p. 298 - 301 (2014/01/17)

A novel series of 1,2,4-triazino-[5,6b]indole-3-thione covalently linked to 7-chloro-4-aminoquinoline have been synthesized and evaluated for their in vitro activity against extracellular promastigote and intracellular amastigote form of Leishmania donovani. Among all tested compounds, compounds 7a and 7b were found to be the most active with IC50 values 1.11, 0.36 μM and selectivity index (SI) values 67, >1111, respectively, against amastigote form of L. donovani which is several folds more potent than the standard drugs, miltefosine (IC50 = 8.10 μM, SI = 7) and sodium stibo-gluconate (IC50 = 54.60 μM, SI ≥ 7).

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