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CAS

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24787-85-7

Z-MET-ALA-OH, with the molecular formula C15H22N2O4S, is a synthetic chemical compound derived from the natural amino acid L-alanine. It features a Z-methyl group attached to the sulfur atom, distinguishing it from its natural counterpart. Z-MET-ALA-OH is integral in the realms of peptide synthesis and drug development, where it functions as a fundamental building block for the assembly of peptide chains. Its capacity to modulate biological processes and engage with various cellular targets underscores its potential pharmaceutical applications. Furthermore, Z-MET-ALA-OH has garnered interest for its utility in drug delivery systems and as a valuable tool in chemical biology research, thereby significantly contributing to the advancement of peptide-based therapeutics.
Usage:
Used in Pharmaceutical Industry:
Z-MET-ALA-OH is used as a building block in peptide synthesis for the development of novel pharmaceuticals, leveraging its ability to modulate biological processes and interact with cellular targets.
Used in Drug Development:
Z-MET-ALA-OH is utilized as a component in the creation of peptide-based drugs, contributing to the discovery and design of new therapeutic agents.
Used in Drug Delivery Systems:
Z-MET-ALA-OH is employed in the formulation of drug delivery systems to enhance the efficacy and targeted delivery of peptide-based therapeutics.
Used in Chemical Biology Research:
Z-MET-ALA-OH serves as a research tool in chemical biology, aiding in the exploration of peptide interactions and the mechanisms of biological processes.

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  • 24787-85-7 Structure

  • Basic information

    1. Product Name: Z-MET-ALA-OH
    2. Synonyms: Z-MET-ALA-OH
    3. CAS NO:24787-85-7
    4. Molecular Formula: C16H22N2O5S
    5. Molecular Weight: 354.42
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 24787-85-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 642.4°C at 760 mmHg
    3. Flash Point: 342.3°C
    4. Appearance: /
    5. Density: 1.257g/cm3
    6. Vapor Pressure: 2.22E-17mmHg at 25°C
    7. Refractive Index: 1.561
    8. Storage Temp.: -15°C
    9. Solubility: N/A
    10. CAS DataBase Reference: Z-MET-ALA-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: Z-MET-ALA-OH(24787-85-7)
    12. EPA Substance Registry System: Z-MET-ALA-OH(24787-85-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 24787-85-7(Hazardous Substances Data)

24787-85-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 24787-85-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,7,8 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 24787-85:
(7*2)+(6*4)+(5*7)+(4*8)+(3*7)+(2*8)+(1*5)=147
147 % 10 = 7
So 24787-85-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H22N2O5S/c1-11(15(20)21)17-14(19)13(8-9-24-2)18-16(22)23-10-12-6-4-3-5-7-12/h3-7,11,13H,8-10H2,1-2H3,(H,17,19)(H,18,22)(H,20,21)

24787-85-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Z-MET-ALA-OH

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:24787-85-7 SDS

24787-85-7Relevant articles and documents

The efficient preparation of di- and tripeptides by coupling N-(Cbz- or Fmoc-α-aminoacyl)benzotriazoles with unprotected amino acids

Katritzky, Alan R.,Angrish, Parul,Suzuki, Kazuyuki

, p. 411 - 424 (2007/10/03)

N-(Cbz- or Fmoc-α-aminoacyl)benzotriazoles 2 and N-protected peptidoylbenzotriazoles 6 are coupled in aqueous acetonitrile solution with free amino acids or dipeptides to prepare: (i) 22 chirally pure dipeptides 5a-v (in an average yield of 82%) from N-(Cbz- or Fmoc-α-aminoacyl)benzotriazoles 2 and unprotected amino acids, (ii) five chiral tripeptides 7a-e (in an average yield of 75%) from N-protected peptidoylbenzotriazoles 6 and unprotected amino acids, (iii) one chiral tripeptide 7g (62%) from N-(Cbz- or Fmoc-α- aminoacyl)benzotriazole 2a and the free dipeptide 8. In all, N-(Cbz- or Fmoc-α-aminoacyl)benzotriazole derivatives of 17 of the 20 naturally occurring amino acids were used, including those containing the following unprotected side chain functionalities: alcoholic -OH (Ser), indole -NH (Trp), imidazole -NH, phenolic -OH (Tyr), -CONH2 (Gln, Asn), -SH (Cys), -CO2H (Glu, Asp), and -S-S (Cystine). Support for the complete retention of chirality was obtained by parallel experiments involving D-Ala, L-Ala, and DL-Ala for the preparation of di- and tripeptides. This and other evidence for chiral integrity was supported by NMR and HPLC analyses. Georg Thieme Verlag Stuttgart.

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