Chiral pool synthesis of 4a-substituted carbocyclic cyclopentanoid nucleoside precursors, I
A suitable protected D-ribono-1,4-lactone derivative has been used for the straightforward chiral pool synthesis of cyclopentanoid nucleoside precursors. Thus, epoxidation followed by deoxygenation or regioselective ring opening led to nucleoside precurso
Csuk, Rene,Doerr, Petra,Kuehn, Martin,Krieger, Claus,Antipin, Mikhael Y.