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2-(Aminomethyl)phenyl boronic acid is a boronic acid derivative with the molecular formula C7H10BNO2. It features a phenyl group with an aminomethyl functional group attached to the boron atom, making it a versatile compound in various chemical and pharmaceutical applications.

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  • 248274-03-5 Structure
  • Basic information

    1. Product Name: 2-(AMINOMETHYL)PHENYL BORONIC ACID
    2. Synonyms: 2-(AMINOMETHYL)PHENYL BORONIC ACID
    3. CAS NO:248274-03-5
    4. Molecular Formula: C7H10BNO2
    5. Molecular Weight: 150.97
    6. EINECS: N/A
    7. Product Categories: Boronate Ester;Boronic Acid;Potassium Trifluoroborate
    8. Mol File: 248274-03-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 354.0±44.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.18±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: 8.23±0.53(Predicted)
    10. CAS DataBase Reference: 2-(AMINOMETHYL)PHENYL BORONIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-(AMINOMETHYL)PHENYL BORONIC ACID(248274-03-5)
    12. EPA Substance Registry System: 2-(AMINOMETHYL)PHENYL BORONIC ACID(248274-03-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 248274-03-5(Hazardous Substances Data)

248274-03-5 Usage

Uses

Used in Organic Synthesis:
2-(Aminomethyl)phenyl boronic acid is used as a building block in organic synthesis for the preparation of various biologically active compounds and pharmaceuticals. Its unique structure allows for the creation of diverse molecules with potential therapeutic properties.
Used in Material Science:
In the field of material science, 2-(Aminomethyl)phenyl boronic acid is utilized in the development of novel materials for electronic and optical applications. Its chemical properties enable the design of advanced materials with improved performance characteristics.
Used in Catalysis:
2-(Aminomethyl)phenyl boronic acid also finds application in the field of catalysis, where it can act as a catalyst or a catalyst precursor in various chemical reactions. Its ability to form stable complexes with other molecules makes it a valuable component in catalytic processes.
Used in Pharmaceutical Industry:
2-(Aminomethyl)phenyl boronic acid has been investigated for its potential as a therapeutic agent for the treatment of cancer and other diseases. Its unique structure allows for the development of targeted drug delivery systems and the modulation of biological pathways, offering new avenues for disease treatment and management.

Check Digit Verification of cas no

The CAS Registry Mumber 248274-03-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,8,2,7 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 248274-03:
(8*2)+(7*4)+(6*8)+(5*2)+(4*7)+(3*4)+(2*0)+(1*3)=145
145 % 10 = 5
So 248274-03-5 is a valid CAS Registry Number.

248274-03-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(aminomethyl)phenyl]boronic acid

1.2 Other means of identification

Product number -
Other names (2-(Aminomethyl)phenyl)boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:248274-03-5 SDS

248274-03-5Relevant articles and documents

BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION

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Paragraph 00497; 00498, (2015/06/11)

Described herein are monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins.

Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors

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Page/Page column 40, (2010/02/15)

Various thienopyrimidine-based analog compounds are able to selectively inhibit the Src family of tyrosine kinases. These compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.

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