A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE
An active for use in the treatment or inhibition of an inflammatory disease associated with over-activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Mal) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or a derivative thereof.
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Paragraph 0078-0084; 0157-0158
(2016/12/01)
One pot direct synthesis of amides or oxazolines from carboxylic acids using Deoxo-Fluor reagent
A mild and highly efficient one pot-one step condensation and/or condensation-cyclization of various acids to amides and/or oxazolines using Deoxo-Fluor reagents is described. Parallel syntheses of various free fatty acids with 2-amino-2,2-dimethyl-1-propanol resulted with excellent yields.
Kangani, Cyrous O.,Kelley, David E.
p. 8917 - 8920
(2007/10/03)
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