250349-13-4 Usage
Uses
Used in Pharmaceutical Industry:
(S)-3-BOC-AMINO-5-(CARBOXYMETHYL)-2,3-DIHYDRO-1,5-BENZOTHIAZEPIN-4(5H)-ONE is used as a chemical intermediate for the development of drugs targeting various medical conditions. Its unique structure and functional groups make it a promising candidate for the creation of novel therapeutic agents.
Used in Drug Synthesis:
In the field of medicinal chemistry, (S)-3-BOC-AMINO-5-(CARBOXYMETHYL)-2,3-DIHYDRO-1,5-BENZOTHIAZEPIN-4(5H)-ONE serves as a key building block for the synthesis of more complex drug molecules. Its BOC-protected amino group and carboxymethyl group can be further modified to create a diverse range of pharmaceutical compounds with specific therapeutic properties.
Used in Research and Development:
(S)-3-BOC-AMINO-5-(CARBOXYMETHYL)-2,3-DIHYDRO-1,5-BENZOTHIAZEPIN-4(5H)-ONE is utilized as a research tool in the study of benzothiazepine chemistry and its potential applications in drug discovery. It can help scientists understand the structure-activity relationships and optimize the design of new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 250349-13-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,0,3,4 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 250349-13:
(8*2)+(7*5)+(6*0)+(5*3)+(4*4)+(3*9)+(2*1)+(1*3)=114
114 % 10 = 4
So 250349-13-4 is a valid CAS Registry Number.
250349-13-4Relevant articles and documents
Design and synthesis of potent bradykinin agonists containing a benzothiazepine moiety
Amblard, Muriel,Daffix, Isabelle,Bedos, Philippe,Bergé, Gilbert,Pruneau, Didier,Paquet, Jean-Luc,Luccarini, Jean-Michel,Bélichard, Pierre,Dodey, Pierre,Martinez, Jean
, p. 4185 - 4192 (1999)
A bradykinin analogue (H-Arg-Pro-Pro-Gly-Phe-Ser-D-BT-Arg-OH, 3) in which the Pro-Phe dipeptide was replaced by the (3S)[amino]-5- (carbonylmethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one (D-BT) moiety has been synthesized. The same modification was perf
Design, synthesis, and biological evaluation of 1,5-benzothiazepine-4-one derivatives targeting factor VIIa/tissue factor
Ayral, Erwan,Gloanec, Philippe,Berge, Gilbert,de Nanteuil, Guillaume,Mennecier, Philippe,Rupin, Alain,Verbeuren, Tony J.,Fulcrand, Pierre,Martinez, Jean,Hernandez, Jean-Francois
supporting information; scheme or table, p. 1386 - 1391 (2009/10/15)
The 1,5-benzothiazepine-4-one scaffold was earlier shown to provide efficient protease inhibitors. In this contribution, we describe its use in the design of factor VIIa/tissue factor inhibitors. A series containing a scaffold non-substituted on its aryl part led to compound 20 with an IC50 of 2.16 μM. Following molecular modelling studies of this compound, a second series was prepared, which necessitated the synthesis of protected 7- or 8-substituted 1,5-benzothiazepine-4-one derivatives.