251554-29-7Relevant articles and documents
Radical-Polar Crossover Annulation: A Platform for Accessing Polycyclic Cyclopropanes
Milligan, John A.,Burns, Kevin L.,Le, Anthony V.,Polites, Viktor C.,Wang, Zheng-Jun,Molander, Gary A.,Kelly, Christopher B.
supporting information, p. 242 - 247 (2019/12/11)
Photoredox-mediated radical/polar crossover (RPC) processes provide unique solutions to challenging annulations. Herein, we describe an approach to the cyclopropanation of olefins that are embedded within bicyclic scaffolds. Whereas these systems are noto
MACROCYCLIC BENZOFUSED PYRIMIDINE DERIVATIVES
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Page/Page column 137-138, (2008/12/05)
Macrocyclic benzofused pyrimidine compounds, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions are described herein.
Substituted guanidine derivatives and process for producing the same
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Page column 49, (2010/01/31)
A compound represented by the general formula (1): wherein each of R1, R2, R3, R4and R5is a hydrogen atom, an alkyl group, a substituted alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkenyl group, a saturated heterocyclic group, an aromatic group, an acyl group or the like; each of Y1, Y2, Y3and Y4is a single bond, —CH2—, —O—, —CO— or the like, provided that at least two of Y1through Y4are independently a group other than a single bond; and Z may be absent, or one or more Zs may be present and are independently an alkyl group, a substituted alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkenyl group, a saturated heterocyclic group, a halogen atom, a carboxyl group, an alkoxycarbonyl group, an aromatic group, an acyl group or the like, is useful as a therapeutic or prophylactic agent for diseases caused by the acceleration of the sodium/proton exchange transport system.
