Exploring the synthesis of masked phosphoramido 6-vinylcytidine derivatives as building blocks for cross-linking oligonucleotides
In the present work the synthesis of building blocks (2a,b), bearing a masked form of the reactive vinyl group bound to the C-6 position of a cytidine derivative, has been studied. The understanding of byproduct formation together with conformational considerations let us to plan a straightforward approach for the synthesis of the target compounds.
Radi, Marco,Spinosa, Raffaella,Parlato, Maria Cristina,Corelli, Federico,Botta, Maurizio
p. 151 - 166
(2008/02/09)
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