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(S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid is a complex organic compound featuring a propanoic acid backbone with a trityloxy group and a tert-butoxycarbonyl (Boc) protected amino group at the second carbon atom. The Boc group acts as a protective agent for the amino group, and the trityloxy group shields the hydroxyl group, making this compound a valuable building block in the synthesis of various peptides.

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  • 252897-67-9 Structure
  • Basic information

    1. Product Name: (S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid
    2. Synonyms: (S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid;Boc-Ser(Trt)-OH;N-[(1,1-Dimethylethoxy)carbonyl]-O-(triphenylmethyl)-L-serine
    3. CAS NO:252897-67-9
    4. Molecular Formula: C27H29NO5
    5. Molecular Weight: 447.53096
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 252897-67-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 595.8±50.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.182±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 3.44±0.10(Predicted)
    10. CAS DataBase Reference: (S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: (S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid(252897-67-9)
    12. EPA Substance Registry System: (S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid(252897-67-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 252897-67-9(Hazardous Substances Data)

252897-67-9 Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid is used as a key building block in peptide synthesis for the development of pharmaceuticals. Its protected groups allow for controlled reactions in the synthesis process, ensuring the formation of the desired peptide sequences with minimal side reactions or degradation.
Used in Research and Development:
In the field of research and development, (S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid is utilized for the synthesis of novel peptides with potential therapeutic applications. Its unique structure allows for the exploration of new peptide sequences and their biological activities, contributing to the advancement of peptide-based drug discovery.
It is important to handle (S)-2-((tert-Butoxycarbonyl)aMino)-3-(trityloxy)propanoic acid with care due to its potential for causing skin irritation and eye damage, highlighting the need for proper safety measures during its use in both industrial and research settings.

Check Digit Verification of cas no

The CAS Registry Mumber 252897-67-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,8,9 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 252897-67:
(8*2)+(7*5)+(6*2)+(5*8)+(4*9)+(3*7)+(2*6)+(1*7)=179
179 % 10 = 9
So 252897-67-9 is a valid CAS Registry Number.

252897-67-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-trityloxypropanoic acid

1.2 Other means of identification

Product number -
Other names Boc-Ser(Trt)-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:252897-67-9 SDS

252897-67-9Relevant articles and documents

Oxazole and thiazole combinatorial libraries

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Page/Page column 10; Sheet 3, (2008/06/13)

This invention provides a novel method for synthesizing an ensemble of peptides that allows for the generation of an unlimited number of antibiotic compounds. More specifically, the method comprises utilizes synthetic heterocyclic amino acids containing thaizole and/or oxazole as building blocks in a solid phase combinatorial synthesis to yield natural and unnatural antibiotic compounds.

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