- Inorganic alkali catalytic 1, 5 - ketonic ester apperception compound synthesis method
-
The invention discloses a synthesis method for a 1,5-ketonic ester compound under catalyzing of inorganic base. The synthesis method comprises the following steps: taking a compound of the general formula I as a raw material, taking inorganic base as a ca
- -
-
Paragraph 0048-0050
(2017/10/11)
-
- Sequential Michael addition/retro-Claisen condensation of aromatic β-diketones with α,β-unsaturated esters: An approach to obtain 1,5-ketoesters
-
A K2CO3-catalyzed one-pot protocol involving sequential C-C bond formation and cleavage of aromatic β-diketones with α,β-unsaturated esters is developed to obtain 1,5-ketoesters. The sequential reaction via Michael addition and retro-Claisen condensation proceeds smoothly under mild conditions in up to 98% isolated yield. The mechanism study disclosed that the cascade process involved C-C bond cleavage of aromatic β-diketone as a phenacyl donor under alcoholic alkalescent conditions.
- Cai, Gui-Xin,Wen, Jing,Lai, Ting-Ting,Xie, Dan,Zhou, Cheng-He
-
supporting information
p. 2390 - 2394
(2016/03/01)
-
- Synthesis of γ-, δ-, and ε-lactams by asymmetric transfer hydrogenation of N-(tert-butylsulfinyl)iminoesters
-
Highly enantiomerically enriched γ- and δ-lactams have been prepared by a simple and very efficient procedure that involves the asymmetric transfer hydrogenation of N-(tert-butylsulfinyl)iminoesters followed by desulfinylation of the nitrogen atom and spo
- Guijarro, David,Pablo, Oscar,Yus, Miguel
-
p. 3647 - 3654
(2013/05/22)
-
- Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water
-
The combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (VA-044) and the surfactant, cetyltrimethyl-ammonium bromide (CTAB), was found to be the most suitable condition for the effective and direct synthesis of useful active thioesters (pentafluorophenyl thioesters) in water. In addition, the direct amidation of aldehydes was achieved by the addition of the amines to the thioesterification reaction mixture in water.
- Nambu, Hisanori,Hata, Kayoko,Matsugi, Masato,Kita, Yasuyuki
-
p. 719 - 727
(2007/10/03)
-
- Controlling factors determining the regiochemistry of intramolecular alkoxymercuration
-
The intramolecular alkoxymercuration of (E)-5-arylpent-4-en-1-ols indicated that the regioselectivity is closely related to the Hammett constants of the para-substituents on the benzene ring. Large solvent effects on the regioselectivity were also observe
- Senda, Yasuhisa,Kanto, Hiroko,Itoh, Hiroki
-
p. 1143 - 1146
(2007/10/03)
-