255850-24-9

Basic information

• Product Name: 4-ETHYNYL-2,6-DIMETHYL-PHENYLAMINE
• Synonyms: 4-ETHYNYL-2,6-DIMETHYL-PHENYLAMINE;Benzenamine, 4-ethynyl-2,6-dimethyl- (9CI);BenzenaMine, 4-ethynyl-2,6-diMethyl-;4-cyano-2,6-diMethyl-phenylaMine;4-Ethynyl-2,6-dimethylaniline
• CAS NO: 255850-24-9
• Molecular Formula: C₁₀H₁₁N
• Molecular Weight: 145.20104
• Product Categories: AMINEPRIMARY
• Mol File: 255850-24-9.mol

Chemical Properties

• Boiling Point: 267.614°C at 760 mmHg
• Flash Point: 123.912°C
• Appearance: /
• Density: 1.014g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.566
• PKA: 2.81±0.10(Predicted)
• CAS DataBase Reference: 4-ETHYNYL-2,6-DIMETHYL-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHYNYL-2,6-DIMETHYL-PHENYLAMINE(255850-24-9)
• EPA Substance Registry System: 4-ETHYNYL-2,6-DIMETHYL-PHENYLAMINE(255850-24-9)

Safety Data

• Hazardous Substances Data: 255850-24-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H11N/c1-4-9-5-7(2)10(11)8(3)6-9/h1,5-6H,11H2,2-3H3

Upstream product

• 24596-19-8 4-bromo-2,6-dimethylphenylamine 
• 4102-53-8 4-iodo-2,6-dimethylaniline 
• 926895-24-1 2,6-dimethyl-4-[(trimethylsilyl)ethynyl]aniline 
• 255850-23-8 4-(3-hydroxy-3-methylbutynyl)-2,6-dimethylaniline 

Downstream Products

• 640736-61-4 (R)-4-(4-(1-methylheptyloxy)-2,6-dimethylphenylethynyl)-2,6-dimethylphenylisocyanide 
• 640736-49-8 (R)-4-(4-(1-methylheptyloxy)-2,6-dimethylphenylethynyl)-2,6-dimethyl-1-formamidobenzene 
• 640736-48-7 (S)-4-(4-(1-methylhexyloxy-2,6-dimethyl)phenylethynyl)-2,6-dimethyl-1-formamidobenzene 
• 640736-60-3 (S)-4-(4-(1-methylhexyloxy)-2,6-dimethylphenylethynyl)-2,6-dimethylphenylisocyanide 
• 640736-43-2 (S)-4-(4-(1-methylheptyloxy)phenylethynyl)-2,6-dimethyl-1-formamidobenzene 
• 640736-42-1 (R)-4-(4-(1-methylheptyloxy)phenylethynyl)-2,6-dimethyl-1-formamidobenzene 
• 640736-55-6 (S)-4-(4-(1-methylheptyloxy)phenylethynyl)-2,6-dimethylphenylisocyanide 
• 640736-54-5 (R)-4-(4-(1-methylheptyloxy)phenylethynyl)-2,6-dimethylphenylisocyanide 
• 640736-41-0 (S)-4-(4-(1-methylhexyloxy)phenylethynyl)-2,6-dimethyl-1-formamidobenzene 
• 640736-53-4 (S)-4-(4-(1-methylhexyloxy)phenylethynyl)-2,6-dimethylphenylisocyanide 
• 640736-40-9 (S)-4-(4-(1-methylpentyloxy)phenylethynyl)-2,6-dimethyl-1-formamidobenzene 
• 640736-39-6 (R)-4-(4-(1-methylpentyloxy)phenylethynyl)-2,6-dimethyl-1-formamidobenzene 
• 640736-52-3 (S)-4-(4-(1-methylpentyloxy)phenylethynyl)-2,6-dimethylphenylisocyanide 
• 640736-51-2 (R)-4-(4-(1-methylpentyloxy)phenylethynyl)-2,6-dimethylphenylisocyanide 

Relevant articles and documents

Functionalized calix[4]resorcinarene cavitands. Versatile platforms for the modular construction of extended molecular switches

We report the synthesis and investigation of the vase-kite conformational switching of bridged calix[4]resorcinarene-based cavitands bearing iodo or ethynyl substituents on the upper rim of the cavity. These reactive centers make the cavitands versatile p

Assembly and Binding Properties of Osmate Ester-Bridged Binuclear Macrocycles

Osmium (VI)-bridged macrocycles 1a-c, 2, and 3 assemble spontaneously when osmium tetraoxide, olefins, and L-shaped bispyridyl ligands are mixed in CHCl3. The macrocycles possess well-defined square or rectangular cavities enclosed by aryl walls and act as host molecules. Hydrogen-bond donors on the inner surface of the hosts offer binding sites to acceptors of guests with complementary dimensions. The host 1a binds adipamide G2 (Ka = 3.6 × 104 M-1) and terephthalamide G6 (Ka = 2.0 × 104 M-1), while it binds negligibly (Ka -1) benzamide G5, isophthalamide G9, or 1,4-naphthalenedicarboxamide G10. The larger hosts 2 and 3 bind the longer guests biphenyldicarboxamide G12 and terphenyldicarboxamide G17, respectively, but shorter guests such as adipamide G2 and terephthalamide G6 are not well-bound (Ka -1). Hosts 1a-c with different remote substituents (H, OMe, NO2) but identical cavity size were prepared and their binding affinities were measured. The relative binding affinities of the hosts 1a-c to the keto amide G19, ester amide G20, and diester G21 are in the order of 1c (NO2) ? 1a (H) > 1b (OCH3). The substituent effects on the binding strength are interpreted in terms of the electron density at the pyridine nitrogen of the hosts and its effect on bifurcated hydrogen bonding.