256662-98-3Relevant articles and documents
Preparation of a synthetic equivalent of chiral methyl 2,5- dihydroxycyclohexane-1,4-dienecarboxylate
Yoshida, Naoyuki,Konno, Hiroyuki,Kamikubo, Takashi,Takahashi, Michiyasu,Ogasawara, Kunio
, p. 3849 - 3857 (1999)
A chiral tricyclic diol, serving as a synthetic equivalent of chiral methyl 2,5-dihydroxycyclohexane-1,4-dienecarboxylate, has been prepared in both enantiomeric forms by employing a lipase-mediated kinetic resolution in vinyl acetate.
Synthesis of (+)-Epoxydon, (–)-Phyllostine, (–)-RKTS 33, and (–)-Parasitenone Featuring Selective Sulfonylation and Oxirane Ring Closure of Aldol Cyclization Products
Chen, Xiaochuan,Jia, Junhao,Jiang, Yimin,Shui, Feng,Yang, Xing,Zhou, Qin
, (2020/07/04)
Two new synthetic approaches to anhydrogabosines are developed from the polyoxygenated aldol cyclization intermediates, bearing different O-protecting groups, which were transformed to various gabosine-type cyclitols. Selective sulfonylation on the required hydroxyl group of the intermediates and the subsequent oxirane ring closure are employed as the key steps in both approaches, by which (+)-epoxydon, (–)-phyllostine, (–)-RKTS 33, and (–)-parasitenone were synthesized from δ-d-gluconolactone.
Enantioselective total synthesis of polyoxygenated cyclohexanoids: (+)-streptol, ent-RKTS-33 and putative '(+)-parasitenone'. Identity of parasitenone with (+)-epoxydon
Mehta, Goverdhan,Pujar, Shashikant R.,Ramesh, Senaiar S.,Islam, Kabirul
, p. 3373 - 3376 (2007/10/03)
Short, simple and enantioselective syntheses of the natural product (+)-streptol, the non-peptide apoptosis inhibitor ent-RKTS-33 and the putative structure of 'parasitenone' have been accomplished from the readily available chiral building block. 'Parasi
