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Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI) is a heterocyclic organic compound characterized by a molecular formula of C8H6N2O2. It features a unique fused imidazole and pyridine ring system, with a carboxylic acid functional group attached at the 6-position. Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI) holds promise in medicinal chemistry, particularly for the development of pharmaceutical drugs, due to its distinctive structural properties.

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  • 256935-76-9 Structure
  • Basic information

    1. Product Name: Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI)
    2. Synonyms: Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI);H-imidazo[1,5-a]pyridine-6-carboxylic acid;IMIDAZO[1,5-A]PYRIDINE-6-CARBOXYLIC ACID
    3. CAS NO:256935-76-9
    4. Molecular Formula: C8H6N2O2
    5. Molecular Weight: 162.14544
    6. EINECS: N/A
    7. Product Categories: AMINETERTIARY;Heterocycle-Pyridine series
    8. Mol File: 256935-76-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.41
    6. Refractive Index: 1.676
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: 0.80±0.41(Predicted)
    10. CAS DataBase Reference: Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI)(CAS DataBase Reference)
    11. NIST Chemistry Reference: Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI)(256935-76-9)
    12. EPA Substance Registry System: Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI)(256935-76-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 256935-76-9(Hazardous Substances Data)

256935-76-9 Usage

Uses

Used in Pharmaceutical Development:
Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI) is utilized as a building block in the synthesis of various biologically active compounds. Its unique structure allows for the creation of diverse pharmaceutical agents with potential therapeutic applications.
Used in Medicinal Chemistry Research:
Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI) serves as a valuable subject for researchers and chemists to study and understand its properties and potential uses. By exploring its pharmacological activities, Imidazo[1,5-a]pyridine-6-carboxylic acid (9CI) may contribute to the advancement of pharmaceuticals and medicinal chemistry, offering new avenues for drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 256935-76-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,6,9,3 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 256935-76:
(8*2)+(7*5)+(6*6)+(5*9)+(4*3)+(3*5)+(2*7)+(1*6)=179
179 % 10 = 9
So 256935-76-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H6N2O2/c11-8(12)6-1-2-7-3-9-5-10(7)4-6/h1-5H,(H,11,12)

256935-76-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name Imidazo[1,5-a]pyridine-6-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:256935-76-9 SDS

256935-76-9Downstream Products

256935-76-9Relevant articles and documents

Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease

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Page 53, (2010/02/06)

The invention provides compounds of Formula I: 1These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat conditions or diseases in which α7 is known to be involved.

Synthesis and biological evaluation of 2-Indolyloxazolines as a new class of tubulin polymerization inhibitors. Discovery of A-289099 as an orally active antitumor agent

Li, Qun,Woods, Keith W.,Claiborne, Akiyo,Gwaltney, Ii, Stephen L.,Barr, Kenneth J.,Liu, Gang,Gehrke, Laura,Credo,Hui, Yu Hua,Lee, Jang,Warner, Robert B.,Kovar, Peter,Nukkala, Michael A.,Zielinski, Nicolette A.,Tahir, Stephen K.,Fitzgerald, Michael,Kim, Ki H.,Marsh, Kennan,Frost, David,Ng, Shi-Chung,Rosenberg, Saul,Sham, Hing L.

, p. 465 - 469 (2007/10/03)

A series of indole containing oxazolines has been discovered as a result of structural modifications of the lead compound A-105972. The compounds exert their anticancer activity through inhibition of tubulin polymerization by binding at the colchicine site. A-289099 was identified as an orally active antimitotic agent active against various cancer cell lines including those that express the MDR phenotype. The anticancer activity, pharmacokinetics, and an efficient and enantioselective synthesis of A-289099 are described.

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