257294-28-3

Basic information

• Product Name: (E)-Methyl4-(2-iodovinyl)benzoate
• Synonyms: (E)-Methyl4-(2-iodovinyl)benzoate
• CAS NO: 257294-28-3
• Molecular Formula: C₁₀H₉IO₂
• Molecular Weight: 288
• Mol File: 257294-28-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-Methyl4-(2-iodovinyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-Methyl4-(2-iodovinyl)benzoate(257294-28-3)
• EPA Substance Registry System: (E)-Methyl4-(2-iodovinyl)benzoate(257294-28-3)

Safety Data

• Hazardous Substances Data: 257294-28-3(Hazardous Substances Data)

Upstream product

• 75-47-8 iodoform 
• 1571-08-0 methyl 4-formylbenzoate 
• 75-11-6 diiodomethane 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 

Downstream Products

• 410094-54-1 methyl 4-[(1E)-3-diethoxyphosphoryl-3,3-difluoroprop-1-enyl]benzoate 
• 1093190-15-8 (E)-methyl 4-(4-(4-(morpholinomethyl)phenyl)but-1-en-3-ynyl)benzoate 
• 1093190-18-1 (E)-methyl 4-(4-(4-((tert-butyldimethylsilyloxy)methyl)phenyl)but-1-en-3-ynyl)benzoate 
• 115665-79-7 (E)-4-(β-bromovinyl)benzoic acid methyl ester 
• 1093189-92-4 (E)-4-(4-(4-(morpholinomethyl)phenyl)but-1-en-3-ynyl)benzoic acid 

Relevant articles and documents

Gold (I/III)-Catalyzed Trifluoromethylthiolation and Trifluoromethylselenolation of Organohalides

The first C?SCF3/SeCF3 cross-coupling reactions using gold redox catalysis [(MeDalphos)AuCl], AgSCF3 or Me4NSeCF3, and organohalides as substrates are reported. The new methodology enables a one-stop shop synthesis of aryl/alkenyl/alkynyl trifluoromethylthio- and selenoethers with a broad substrate scope (>60 examples with up to 97 % isolated yield). The method is scalable, and its robustness is evidenced by the late-stage functionalization of various bioactive molecules, which makes this reaction an attractive alternative in the synthesis of trifluoromethylthio- and selenoethers for pharmaceutical and agrochemical research and development.

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.