25771-89-5 Usage
Uses
Used in Pharmaceutical Industry:
6,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid ethyl ester is used as a potential active pharmaceutical ingredient for its possible antibacterial, antifungal, anticancer, and anti-inflammatory properties. Its quinoline structure is known to contribute to these biological activities, making it a candidate for the development of new drugs.
Used in Research and Development:
In the field of scientific research, 6,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid ethyl ester is used as a subject of study to explore its physicochemical properties and how they may vary under different conditions such as temperature and pH. This research can lead to a better understanding of the compound's behavior and its potential applications in medicine and other fields.
Used in Drug Delivery Systems:
6,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid ethyl ester may be utilized in the development of drug delivery systems, where its unique structure could be leveraged to improve the delivery, bioavailability, and therapeutic outcomes of associated pharmaceuticals. This could be particularly relevant in the context of targeted therapies where precision in drug delivery is crucial.
Check Digit Verification of cas no
The CAS Registry Mumber 25771-89-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,7 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 25771-89:
(7*2)+(6*5)+(5*7)+(4*7)+(3*1)+(2*8)+(1*9)=135
135 % 10 = 5
So 25771-89-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H9Cl2NO3/c1-2-18-12(17)8-5-15-10-7(11(8)16)3-6(13)4-9(10)14/h3-5H,2H2,1H3,(H,15,16)
25771-89-5Relevant articles and documents
Dichloro-4-quinolinol-3-carboxylic acid: Synthesis and antioxidant abilities to scavenge radicals and to protect methyl linoleate and DNA
Li, Guo-Xiang,Liu, Zai-Qun,Luo, Xu-Yang
experimental part, p. 1821 - 1827 (2010/06/21)
5,7-, 5,8-, 6,8-, 7,8-Dichloro-4-quinolinol-3-carboxylic acid (5,7-, 5,8-, 6,8-, 7,8-DCQA) together with 7-chloro-4-quinolinol-3-carboxylic acid (7-CQA) and 4-quinolinol-3-carboxylic acid (QA) were synthesized to investigate the antioxidant properties. 5,7-DCQA exhibited the highest ability to scavenge 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) cationic radical (ABTS+.), 2,2′-diphenyl-1-picrylhydrazyl (DPPH) and galvinoxyl radicals. 6,8-DCQA possessed the highest efficacy to protect methyl linoleate against 2,2′-azobis(2-amidinopropane)dihydrochloride (AAPH)-induced oxidation. 5,7-, 5,8-DCQA and QA were able to retard the β-carotene-bleaching in β-carotene-linoleic acid emulsion. In addition, 5,8- and 6,8-DCQA efficiently protected DNA against hydroxyl radical (.OH)-mediated oxidation, and 5,8-DCQA and 7-CQA were active to protect DNA against AAPH-induced oxidation. Furthermore, only 7-CQA can protect DNA against Cu2+/glutathione (GSH)-mediated oxidation. Dichloro-4-quinolinol-3-carboxylic acids were potent to be antiradical drugs, and were worthy to be researched pharmacologically.
