- Suzuki-Miyaura and Negishi approaches to a series of forensically relevant pyridines and pyrimidines
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A library of 5-aryl-4-methylpyrimidines, phenyl ring-substituted derivatives of 4-benzylpyrimidines, 2,6-benzylpyridines, and 2,6-dibenzyl-4-methylpyridines were prepared. The synthesis of 5-aryl-4-methylpyrimidines was accomplished by Suzuki-Miyaura cross-coupling reaction between arylboronic acids and 5-bromo-4-methylpyrimidine. The 4-benzylpyrimidines and 2,6-benzylpyridines were synthesized by treatment of 4-bromopyrimidine and 2,6-dibromopyridine derivatives with ring-substituted benzylzinc reagents. Georg Thieme Verlag Stuttgart.
- Blachut, Dariusz,Szawkalo, Joanna,Czarnocki, Zbigniew
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experimental part
p. 3496 - 3506
(2011/12/04)
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