261350-50-9

Basic information

• Product Name: 5-Isoxazolecarboxylicacid,4-methyl-,ethylester(9CI)
• Synonyms: 5-Isoxazolecarboxylicacid,4-methyl-,ethylester(9CI)
• CAS NO: 261350-50-9
• Molecular Formula: C7H9NO3
• Molecular Weight: 155.15
• Product Categories: CARBOXYLICESTER;OXAZOLE
• Mol File: 261350-50-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Isoxazolecarboxylicacid,4-methyl-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoxazolecarboxylicacid,4-methyl-,ethylester(9CI)(261350-50-9)
• EPA Substance Registry System: 5-Isoxazolecarboxylicacid,4-methyl-,ethylester(9CI)(261350-50-9)

Safety Data

• Hazardous Substances Data: 261350-50-9(Hazardous Substances Data)

Upstream product

• 39910-31-1 ethyl 2-diazo-3-hydroxy-3-methylbutanoate 
• 126580-11-8 ethyl 2-diazo-3-methyl-3-butenoate 
• 121781-57-5 (E)-1,1,1-trichloro-4-ethoxy-3-methylbut-3-en-2-one 
• 64-17-5 ethanol 

Downstream Products

• 1607024-83-8 (4-methylisoxazol-5-yl)methanol 

Relevant articles and documents

Intermolecular [5 + 1]-Cycloaddition between Vinyl Diazo Compounds and tert-Butyl Nitrite to 1,2,3-Triazine 1-Oxides and Their Further Transformation to Isoxazoles

1,2,3-Triazine 1-oxides are formed by nitrosyl addition from tert-butyl nitrite to the vinylogous position of vinyl diazo compounds. This transformation, which is a formal intermolecular [5 + 1] cycloaddition, occurs under mild conditions, with high funct

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.

A convenient one-pot synthesis of 5-carboxyisoxazoles: Trichloromethyl group as a carboxyl group precursor

The one-pot synthesis of ten 5-carboxyisoxazoles from the cyclocondensation of β-alkoxyvinyl trichloromethyl ketones [CCl3C(O)C(R2)=C(R1)OR, where R1, R2=H, Me and R=Me, Et] and 2- trichloroacetyl cyclohexanone with hydroxylamine is reported. This work shows that the trichloromethyl group attached to β-alkoxyvinyl trichloromethyl ketones (a heterocyclic CCC building block) is an excellent carboxyl group precursor.