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1-methylpyrrolidine-2-methylamine, also known as N-methyl-2-methylpyrrolidine, is a chemical compound that belongs to the class of alkylamines. It is a clear, colorless liquid with a pungent odor, known for its solvency and reactivity, making it a versatile and important chemical in various industries.

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  • 26171-06-2 Structure
  • Basic information

    1. Product Name: 1-methylpyrrolidine-2-methylamine
    2. Synonyms: 1-Methyl-2-pyrrolidinemethanamine;1-(1-methylpyrrolidin-2-yl)methanamine;1-(1-methylpyrrolidin-2-yl)methanamine(SALTDATA: 2HCl);2-Aminomethyl-1-methylpyrrolidine;1-Methyl-2-aMinoMethyl-pyrrolidine;(1-methyl-2-pyrrolidinyl)methanamine;1-Methyl-2-pyrrolidinemethanamine 2HCl;1-methylpyrrolidine-2-methylamine
    3. CAS NO:26171-06-2
    4. Molecular Formula: C6H14N2
    5. Molecular Weight: 114.18876
    6. EINECS: 247-496-7
    7. Product Categories: N/A
    8. Mol File: 26171-06-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 126.7 °C at 760 mmHg
    3. Flash Point: 32.7 °C
    4. Appearance: /
    5. Density: 0.917 g/cm3
    6. Vapor Pressure: 11.5mmHg at 25°C
    7. Refractive Index: 1.473
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    9. Solubility: N/A
    10. PKA: 9.97±0.40(Predicted)
    11. CAS DataBase Reference: 1-methylpyrrolidine-2-methylamine(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1-methylpyrrolidine-2-methylamine(26171-06-2)
    13. EPA Substance Registry System: 1-methylpyrrolidine-2-methylamine(26171-06-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 26171-06-2(Hazardous Substances Data)

26171-06-2 Usage

Uses

Used in Pharmaceutical Industry:
1-methylpyrrolidine-2-methylamine is used as a solvent and an intermediate in the production of pharmaceuticals for its ability to dissolve a wide range of substances and facilitate chemical reactions, contributing to the synthesis of various medications.
Used in Agrochemical Industry:
1-methylpyrrolidine-2-methylamine is used as a solvent and intermediate in the production of agrochemicals, enabling the creation of effective compounds for agricultural applications, such as pesticides and fertilizers.
Used in Specialty Chemicals Synthesis:
1-methylpyrrolidine-2-methylamine is used as a key component in the synthesis of specialty chemicals, where its solvency and reactivity are crucial for the development of unique and high-performance products.
Used in Research and Development:
1-methylpyrrolidine-2-methylamine is utilized in research and development settings as a versatile chemical for exploring new reactions and creating novel compounds, further expanding its applications across different fields.
It is essential to handle and store 1-methylpyrrolidine-2-methylamine with care, as it can be hazardous if not used properly, highlighting the need for proper safety measures during its application in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 26171-06-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,1,7 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 26171-06:
(7*2)+(6*6)+(5*1)+(4*7)+(3*1)+(2*0)+(1*6)=92
92 % 10 = 2
So 26171-06-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H14N2/c1-8-4-2-3-6(8)5-7/h6H,2-5,7H2,1H3

26171-06-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (1-methylpyrrolidin-2-yl)methanamine

1.2 Other means of identification

Product number -
Other names EINECS 247-496-7

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:26171-06-2 SDS

26171-06-2Relevant articles and documents

Synthesis, characterisation and in vitro cytotoxicity studies of a series of chiral platinum(II) complexes based on the 2-aminomethylpyrrolidine ligand: X-ray crystal structure of [PtCl2(R-dimepyrr)] (R-dimepyrr = N-dimethyl-2(R)-aminomethylpyrrolidine)

Diakos, Connie I.,Zhang, Mei,Beale, Philip J.,Fenton, Ronald R.,Hambley, Trevor W.

scheme or table, p. 2807 - 2814 (2009/10/10)

A series of platinum(II) complexes were synthesised based on the enantiomerically pure amino acid proline. Novel synthetic pathways were developed, adapted from standard peptide chemistry, to produce the 2-aminomethylpyrrolidine (pyrr) ligand and its derivatives with differing arrangements of methyl substituents at the exocyclic amine sites. The crystal structure of [PtCl2(R-dimepyrr)] (R-dimepyrr = N,N-dimethyl-2(R)-aminomethylpyrrolidine) is reported and the five-membered ligand ring has been shown to be in an envelope conformation. Cytotoxicity studies were carried out on the ovarian cancer A2780 tumour cell line and its cisplatin-resistant variant, A2780cisR. Remarkably good activity was seen for several of the drugs when compared to cisplatin despite the addition of substantial steric bulk to the amine groups, and there was a lack of cross-resistance with cisplatin seen for some compounds.

Isothiazolecarboxylic acid derivatives and their use as microbicides

-

, (2008/06/13)

Novel isothiazolecarboxylic acid derivatives of the formula (I), in which A, Q, Z and k have the meanings mentioned in the specification, processes for the preparation of the new compounds and their use as microbicides.

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