261909-88-0

Basic information

• Product Name: L-Alanine, cyclopentyl ester (9CI)
• Synonyms: L-Alanine, cyclopentyl ester (9CI)
• CAS NO: 261909-88-0
• Molecular Formula: C₈H₁₅NO₂
• Molecular Weight: 157.2102
• Product Categories: METHOXY;GLYCINESCAFFOLD
• Mol File: 261909-88-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Alanine, cyclopentyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine, cyclopentyl ester (9CI)(261909-88-0)
• EPA Substance Registry System: L-Alanine, cyclopentyl ester (9CI)(261909-88-0)

Safety Data

• Hazardous Substances Data: 261909-88-0(Hazardous Substances Data)

Downstream Products

• 957142-58-4 C₁₇H₂₂ClNO₅S 
• 1221965-62-3 cyclopentyl N-(4-iodobenzyl)-L-alaninate 
• 1439900-90-9 (2S)-cyclopentyl 2-(((((2R,3S,4R,5R)-4-((tert-butoxycarbonyl)amino)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)-phosphoryl)amino)propanoate 
• 1439900-91-0 (2S)-cyclopentyl 2-(((((2R,3S,4R,5R)-4-((tert-butoxycarbonyl)amino)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)-phosphoryl)amino)propanoate 
• 1439900-96-5 (2S)-cyclopentyl 2-(((((2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-amino)propanoate 
• 957142-59-5 C₁₇H₂₁BrClNO₅S 
• 261909-90-4 (2S)-cyclopentyl 2-((chloro(phenoxy)phosphoryl)amino)propanoate 
• 1439900-94-3 (2S)-cyclopentyl 2-(((((2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-amino)propanoate 

Relevant articles and documents

INHIBITORS OF HSP90

The invention provides a compound which is (a) a pyrrolopyrimidine derivative of formula (I) or a tautomer thereof, or (b) a pharmaceutically acceptable salt, N-oxide, hydrate or solvate thereof: Formula (I) wherein R1, R2, R3/

P38 MAP KINASE INHIBITORS

Compounds of formula (I) are inhibitors of p38 MAP kinase, and are therefore of utility in the treatment of, inter alia, inflammatory conditions including rheumatoid arthritis and COPD: formula (I) wherein: G is -N= or -CH=; D is an optionally substituted divalent mono- or bi-cyclic aryl or heteroaryl radical having 5 - 13 ring members; R6 is hydrogen or optionally substituted C1-C3 alkyl; P represents hydrogen and U represents a radical of formula (IA); or U represents hydrogen and P represents a radical of formula -A-(CH2)z-X1-L1 -Y-NH-CHR1R2 wherein A represents an optionally substituted divalent mono- or bicyclic carbocyclic or heterocyclic radical having 5 - 13 ring members; z, Y, L1, and X1 are as defined in the specification; R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intracellular esterase enzymes to a carboxylic acid group; and R2 is the side chain of a natural or non-natural alpha amino acid.

THIAZOLE DERIVATIVES AS INHIBITORS OF P13 KINASE

Compounds of formula (I) are inhibitors of P13 kinase activity, and useful in treatment of, inter alia, autoimmune, inflammatory and proliferative diseases: wherein: s is 0 or 1; U is hydrogen or halogen; X is -(C=O), an optionally substituted divalent ph