261943-47-9

Basic information

• Product Name: 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC
• Synonyms: 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC;7-Diethylaminocoumarin-3 carboxylic acid imidazolide;1-[[7-(Diethylamino)-2-oxo-2H-1-benzopyran-3-yl]carbonyl]-1H-imidazole;7-(Diethylamino)-3-(imidazol-1-ylcarbonyl)-1-benzopyran-2-one
• CAS NO: 261943-47-9
• Molecular Formula: C₁₇H₁₇N₃O₃
• Molecular Weight: 311.339
• Mol File: 261943-47-9.mol

Chemical Properties

• Boiling Point: 558.3±60.0 °C(Predicted)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• PKA: 2.80±0.10(Predicted)
• CAS DataBase Reference: 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC(261943-47-9)
• EPA Substance Registry System: 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC(261943-47-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 261943-47-9(Hazardous Substances Data)

Usage

Uses

Used in Analytical Chemistry:
7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC is used as a fluorescent derivatization reagent for the detection and analysis of hydroxyl groups in various compounds. Its application in the circular dichroic exciton method allows for the identification and quantification of hydroxyl-containing molecules under mild conditions, making it a valuable tool in analytical chemistry.
Used in Fluorescence Labeling:
7-(Diethylamino)-3-(imidazol-1-ylcarbonyl)-1-benzopyran-2-one, a derivative of 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC, is used as a reagent for labeling hydroxy compounds with fluorescent tags. This labeling process enhances the visibility and detection of these compounds, particularly in research and diagnostic applications where the study of hydroxy-containing molecules is crucial.

Upstream product

• 50995-74-9 7-(diethylamino)coumarin-3-carboxylic acid 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 892756-25-1 7-N,N-diethylamino-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]coumarin 
• 892754-02-8 7-(diethylamino)-3-(3-phenyl-1,2,4-oxadiazol-5-yl)-2H-chromen-2-one 

Relevant articles and documents

A novel coumarin-type derivatizing reagent of alcohols: Application in the CD exciton chirality method for microscale structural determination

(Equation Presented) Imidazolide 1 has been prepared from 7-diethylaminocoumarin-3-carboxylic acid (2) and 1,1′-carbonyldiimidazole. This novel fluorescent derivatization reagent can be used in CD exciton chirality method for microscale structural determi

Isomeric 3-isoxadiazolylcoumarins and their derivatives

Here, we represent preparative methods of synthesis of isomeric 3-isoxadiazolylcoumarins and their derivatives. Two new synthetic methods have been developed for 3-[1,2,4-oxadiazol-5-yl]coumarins I. The first method is based on a three-component condensation of coumarin-;3-carboxylic acids, 1,1'-carbonyldiimidazole, and amidoximes. The second method essentially uses the interaction of 5-cyanomethyl-1,2,4-oxadiazoles with salicylic aldehydes. General approach for preparation of 3-[1,2,4-oxadiazol-3-yl]coumarins II has been worked out. Moreover, aforementioned synthetic ways open the way for the synthesis of 2-iminoderivatives III and IV not described before, those were diversified by reaction of nucleophilic substitution of 2-imino group with a numerous amino compounds.