INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION
Compounds of Formula (I) and methods of inhibiting the replication of viruses in a biological sample or patient, of reducing the amount of viruses in a biological sample or patient, and of treating a virus infection in a patient, comprising administering to said biological sample or patient an effective amount of a compound represented by Formula (I), a compound of Table A or B or a pharmaceutically acceptable salt thereof.
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Paragraph 002054-002056
(2021/10/15)
Enantioselective Iridium-Catalyzed Allylation of Nitroalkanes: Entry to β-Stereogenic α-Quaternary Primary Amines
The first systematic study of simple nitronate nucleophiles in iridium-catalyzed allylic alkylation is described. Using a tol-BINAP-modified π-allyliridiumC,O-benzoate catalyst, α,α-disubstituted nitronates substitute racemic branched alkyl-substituted al
Jung, Woo-Ok,Mai, Binh Khanh,Spinello, Brian J.,Dubey, Zachary J.,Kim, Seung Wook,Stivala, Craig E.,Zbieg, Jason R.,Liu, Peng,Krische, Michael J.
supporting information
p. 9343 - 9349
(2021/07/19)
Direct and Efficient Preparation of gem-Chloronitro Compounds or Nitro Compounds from gem-Bromonitro Compounds
Sodiumethanethiolate in methanol is an efficient reducing agent for gem-bromonitro compounds; treatment of the resultant nitronates with a protic acid or with N-chlorosuccinimide gives high yields of the corresponding nitro or gem-chloronitro compounds, respectively.
Amrollah-Madjdabadi, A.,Beugelmans, R.,Lechevallier, A.
p. 826 - 828
(2007/10/02)
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