Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein
A series of novel N,N-disubstituted trifluoro-3-amino-2-propanols has been prepared as potent inhibitors of cholesteryl ester transfer protein (CETP). Modifying the aromatic 3-tetrafluoroethoxy group in the lead molecule 1a with various heteroaryl moietie
Massa, Mark A.,Spangler, Dale P.,Durley, Richard C.,Hickory, Brian S.,Connolly, Daniel T.,Witherbee, Bryan J.,Smith, Mark E.,Sikorski, James A.
p. 1625 - 1628
(2007/10/03)
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