26371-48-2

Basic information

• Product Name: 6-Chloro-3-chromanone
• Synonyms: 6-ChlorochroMan-3-one;6-Chloro-3-chromanone;6-chloro-2H-chroMen-3(4H)-one
• CAS NO: 26371-48-2
• Molecular Formula: C9H7ClO2
• Molecular Weight: 182.60368
• Mol File: 26371-48-2.mol

Chemical Properties

• Boiling Point: 324.041°C at 760 mmHg
• Flash Point: 150.845°C
• Appearance: /
• Density: 1.345g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 6-Chloro-3-chromanone(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-3-chromanone(26371-48-2)
• EPA Substance Registry System: 6-Chloro-3-chromanone(26371-48-2)

Safety Data

• Hazardous Substances Data: 26371-48-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
6-Chloro-3-chromanone is used as a chemical building block for the synthesis of novel organic compounds, contributing to the development of new materials and chemical entities.
Used in Pharmaceutical Development:
6-Chloro-3-chromanone is used as a starting material in the development of pharmaceuticals, leveraging its potential biological activity for therapeutic applications.
Used in Chemical Research:
6-Chloro-3-chromanone is utilized in chemical research to explore its reactivity, properties, and potential for creating new chemical entities, further expanding its applications in the scientific community.

InChI:InChI=1/C9H7ClO2/c10-7-1-2-9-6(3-7)4-8(11)5-12-9/h1-3H,4-5H2

Upstream product

• 115997-75-6 6-Chloro-1a,7b-dihydro-2H-1,3-dioxa-cyclopropa[a]naphthalene 
• 83823-06-7 6-chloro-2H-1-benzopyran-3-carboxylic acid 

Downstream Products

• 744982-80-7 6-chloro-chroman-3-ylamine 

Relevant articles and documents

PHOTOCHEMICAL BEHAVIOUR OF 3,4-EPOXYPRECOCENE-I AND RELATED EPOXYCHROMANS

A systematic study of photochemical behaviour of 3,4-epoxyprecocene-I and related epoxychromans was undertaken.Upon irradiation in acetone or cyclohexane, 3,4-epoxyprecocene-I 1 was found to undergo photoisomerisation to the corresponding 3-chromanone 2.In contrast, the photochemical behaviour of analogous 3,4-dihydro-3,4-epoxy-2H-1-benzopyrans 3 was found to be dependent upon the nature of solvent.Irradiation of 3 in cyclohexane led to photodecarbonylation leading to the formation of 2,3-dihydrobenzofurans 4, whereas irradiation in acetone resulted in the formation of chromanones 5.

ANTAGONISTS OF THE TRPV1 RECEPTOR AND USES THEREOF

The present application is directed to compounds that are TRPV1 antagonists and have formula (I) wherein variables Ar1, L1, R1, R2, R3, R4, R5, Y1, Y2, and Y3, are as defined in the description, which are useful for treating disorders caused by or exacerbated by vanilloid receptor activity.