A new member of the fusaricidin family - Structure elucidation and synthesis of fusaricidin E
Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the suggested stereochemistry. The synthesis was based on a new strategy which includes an efficient access to the 15-guanidino-3-hydroxypentadecanoyl (GHPD) side chain from erucamide.
Reimann, Marcel,Sandjo, Louis P.,Antelo, Luis,Thines, Eckhard,Siepe, Isabella,Opatz, Till