This application relates to novel compounds of formula I (and their pharmaceutically acceptable salts), as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula I, and the
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Example 3
(2010/01/31)
Antithrombotic agents
This application relates to novel compounds of formula I (and their pharmaceutically acceptable salts), as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula I, and the
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(2008/06/13)
1,2-disubstituted indole, azaindole and benzimidazole derivatives possessing amine moiety: A novel series of thrombin inhibitors
A novel series of 1,2-disubstituted indole, azaindole and benzimidazole derivatives possessing an amine moiety was identified as thrombin inhibitors. An indole with basic diamine moieties (12a) was the most potent thrombin inhibitor in the series with K(ass) = 197 x 106 L/mol. (C) 2000 Elsevier Science Ltd.
Takeuchi, Kumiko,Bastian, Jolie A.,Gifford-Moore, Donetta S.,Harper, Richard W.,Miller, Shawn C.,Mullaney, Jeffrey T.,Sall, Daniel J.,Smith, Gerald F.,Zhang, Minsheng,Fisher, Matthew J.
p. 2347 - 2351
(2007/10/03)
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