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Di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), which is a selective and competitive HMG-CoA reductase inhibitor. di(2-Hydroxy Atorvastatin) CalciuM Salt plays a crucial role in the regulation of cholesterol and triglyceride levels in the body, making it a significant pharmaceutical compound for the treatment of hypercholesterolemia.

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  • calcium bis(7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-5-isopropyl-3-phenylpyrrol-1-yl]-3,5-dihydroxyheptanoate)

    Cas No: 265989-46-6

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  • 265989-46-6 Structure
  • Basic information

    1. Product Name: di(2-Hydroxy Atorvastatin) CalciuM Salt
    2. Synonyms: di(2-Hydroxy Atorvastatin) CalciuM Salt;2-Hydroxy Atorvastatin CalciuM Salt;2-Hydroxy Atorvastatin Sodium;Atorvastatin Impurity K
    3. CAS NO:265989-46-6
    4. Molecular Formula: C66H70CaF2N4O12
    5. Molecular Weight: 1189.3564064
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 265989-46-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. Stability: Hygroscopic
    10. CAS DataBase Reference: di(2-Hydroxy Atorvastatin) CalciuM Salt(CAS DataBase Reference)
    11. NIST Chemistry Reference: di(2-Hydroxy Atorvastatin) CalciuM Salt(265989-46-6)
    12. EPA Substance Registry System: di(2-Hydroxy Atorvastatin) CalciuM Salt(265989-46-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 265989-46-6(Hazardous Substances Data)

265989-46-6 Usage

Uses

Used in Pharmaceutical Industry:
Di(2-Hydroxy Atorvastatin) Calcium Salt is used as a cholesterol-lowering agent for patients with hypercholesterolemia. It functions by inhibiting HMG-CoA reductase, an enzyme responsible for the production of cholesterol in the liver. This inhibition leads to a reduction in both elevated LDL-cholesterol and triglyceride levels, thereby helping to manage and treat hypercholesterolemia.
Additionally, as a metabolite of Atorvastatin Calcium Salt, Di(2-Hydroxy Atorvastatin) Calcium Salt may also be utilized in research and development for further understanding the pharmacological properties and potential applications of Atorvastatin and its derivatives in the treatment of various cardiovascular diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 265989-46-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,5,9,8 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 265989-46:
(8*2)+(7*6)+(6*5)+(5*9)+(4*8)+(3*9)+(2*4)+(1*6)=206
206 % 10 = 6
So 265989-46-6 is a valid CAS Registry Number.

265989-46-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:265989-46-6 SDS

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