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266360-50-3

2-acetamido-3-(2,6-difluorophenyl)propanoic acid, commonly known as flurbiprofen, is a non-steroidal anti-inflammatory drug (NSAID) with the molecular formula C11H12F2NO3. It possesses analgesic and antipyretic properties and works by inhibiting the production of prostaglandins, which are responsible for inflammation, pain, and fever.

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  • 266360-50-3 Structure

  • Basic information

    1. Product Name: 2-acetaMido-3-(2,6-difluorophenyl)propaNAic acid
    2. Synonyms: 2-acetaMido-3-(2,6-difluorophenyl)propaNAic acid;2-AcetaMido-3-(2,6-difluorophenyl)propanoic acid;N-ACETYL-3-(2,6-DIFLUORO-PHENYL)-DL-ALANINE
    3. CAS NO:266360-50-3
    4. Molecular Formula: C11H11F2NO3
    5. Molecular Weight: 243.2067464
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 266360-50-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-acetaMido-3-(2,6-difluorophenyl)propaNAic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-acetaMido-3-(2,6-difluorophenyl)propaNAic acid(266360-50-3)
    11. EPA Substance Registry System: 2-acetaMido-3-(2,6-difluorophenyl)propaNAic acid(266360-50-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 266360-50-3(Hazardous Substances Data)

266360-50-3 Usage

Uses

Used in Pharmaceutical Industry:
Flurbiprofen is used as an analgesic and anti-inflammatory agent for the treatment of rheumatoid arthritis, osteoarthritis, and other inflammatory conditions. It helps to relieve pain, reduce inflammation, and lower fever in patients.
Used in Ophthalmology:
Flurbiprofen is used as an ocular anti-inflammatory agent in the form of eye drops. It is effective in treating various eye conditions such as postoperative inflammation following cataract surgery and other ocular surgeries.
Used in Topical Applications:
Flurbiprofen is available in topical forms, such as creams and gels, for the treatment of localized inflammation and pain. It can be applied directly to the affected area to provide relief from inflammation and discomfort.

Check Digit Verification of cas no

The CAS Registry Mumber 266360-50-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,6,3,6 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 266360-50:
(8*2)+(7*6)+(6*6)+(5*3)+(4*6)+(3*0)+(2*5)+(1*0)=143
143 % 10 = 3
So 266360-50-3 is a valid CAS Registry Number.

266360-50-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-acetamido-3-(2,6-difluorophenyl)propanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:266360-50-3 SDS

266360-50-3Relevant articles and documents

Synthesis of a complete set of L-difluorophenylalanines, L-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor

Fujita, Tsugumi,Nose, Takeru,Matsushima, Ayami,Okada, Kazushi,Asai, Daisuke,Yamauchi, Yasuko,Shirasu, Naoto,Honda, Takeshi,Shigehiro, Daiki,Shimohigashi, Yasuyuki

, p. 923 - 927 (2007/10/03)

A complete set of difluorophenylalanines in the L-configuration [L- (F2)Phe] (namely, L-(2,3-F2)Phe, L-(2,4-F2)Phe, L-(2,5-F2)Phe, L-(2,6- F2)Phe, L-(3,4-F2)Phe, L-(3,5-F2)Phe) w

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