270596-48-0 Usage
Uses
Used in Pharmaceutical Development:
FMOC-(S)-3-AMINO-5-HEXYNOIC ACID is used as a building block for the synthesis of peptide-based drugs due to its ability to create enantiopure molecules, which is essential for the development of chiral drugs with specific biological activities.
Used in Peptide Synthesis:
In the field of organic chemistry, FMOC-(S)-3-AMINO-5-HEXYNOIC ACID is used as a protected amino acid for controlled peptide synthesis. The FMOC protecting group allows for selective deprotection, enabling the stepwise assembly of complex peptide sequences.
Used in Drug Development Research:
FMOC-(S)-3-AMINO-5-HEXYNOIC ACID is utilized as a research tool for studying the structure-activity relationships of bioactive peptides. This helps in understanding how the molecular structure of peptides influences their biological activity, which is vital for the design of new therapeutic agents.
Used in the Synthesis of Chiral Molecules:
In the chemical industry, FMOC-(S)-3-AMINO-5-HEXYNOIC ACID is used as a precursor for the synthesis of chiral molecules. The chiral center allows for the creation of enantiomers, which can have different biological activities and are important in the development of enantiomerically pure drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 270596-48-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,0,5,9 and 6 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 270596-48:
(8*2)+(7*7)+(6*0)+(5*5)+(4*9)+(3*6)+(2*4)+(1*8)=160
160 % 10 = 0
So 270596-48-0 is a valid CAS Registry Number.
InChI:InChI=1/C21H19NO4/c1-2-7-14(12-20(23)24)22-21(25)26-13-19-17-10-5-3-8-15(17)16-9-4-6-11-18(16)19/h1,3-6,8-11,14,19H,7,12-13H2,(H,22,25)(H,23,24)/t14-/m0/s1
270596-48-0Relevant articles and documents
Azide- and alkyne-functionalised α- And β3-amino acids
Sminia, Tjerk Jacco,Pedersen, Daniel Sejer
, p. 2643 - 2646,4 (2012/12/13)
The synthesis and full characterisation of bifunctional β3-amino acids that have side chains functionalised with terminal azides (S)-4 and (R)-4 or acetylenes 5 and 6 is reported for the first time. The building blocks incorporate a turn-inducing β3-segment and a side chain that can be functionalised further, for example, through copper-catalysed Huisgen cycloaddition. Moreover, the corresponding α-amino acids 1 and 3 have been synthesised and characterised. All amino acid building blocks were of high optical purity as demonstrated by derivatisation and subsequent NMR analysis.
Azide- and alkyne-functionalised α- And β3-amino acids
Sminia, Tjerk Jacco,Pedersen, Daniel Sejer
, p. 2643 - 2646 (2013/01/15)
The synthesis and full characterisation of bifunctional β3-amino acids that have side chains functionalised with terminal azides (S)-4 and (R)-4 or acetylenes 5 and 6 is reported for the first time. The building blocks incorporate a turn-inducing β3-segment and a side chain that can be functionalised further, for example, through copper-catalysed Huisgen cycloaddition. Moreover, the corresponding α-amino acids 1 and 3 have been synthesised and characterised. All amino acid building blocks were of high optical purity as demonstrated by derivatisation and subsequent NMR analysis. Georg Thieme Verlag KG Stuttgart · New York.
